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Anti-Fibrillarin Antibody

Rabbit polyclonal antibody to Fibrillarin from ABclonal (A0158).
Name: Anti-Fibrillarin Antibody
Description: Rabbit polyclonal antibody to Fibrillarin.
Applications: WB
Dilutions: WB: 1:500 - 1:1000.
Reactivity: Human
Immunogen: A synthetic peptide of human FBL.
Protein Length: 321
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Affinity purification.
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins. Involved in pre-rRNA processing by catalyzing the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. Also acts as a protein methyltransferase by mediating methylation of 'Gln-105' of histone H2A (H2AQ104me), a modification that impairs binding of the FACT complex and is specifically present at 35S ribosomal DNA locus (PubMed:24352239).
Sequence Similarities: Belongs to the methyltransferase superfamily. Fibrillarin family.
Post-Translational Modification: By homology to other fibrillarins, some or all of the N-terminal domain arginines are modified to asymmetric dimethylarginine (DMA).
Cellular Location: Nucleus > Nucleolus.

Fibrillar region of the nucleolus.
UniProt: P22087
Gene ID: 2091
Synonyms: 34 kD nucleolar scleroderma antigen Antibody
34 kDa nucleolar scleroderma antigen Antibody
Fbl Antibody
FBRL_HUMAN Antibody
FIB Antibody
FIB1 Antibody
FLRN Antibody
Histone-glutamine methyltransferase Antibody
Nop1p Antibody
RNA U3 small nucleolar interacting protein 1 Antibody
RNU3IP1 Antibody
rRNA 2' O methyltransferase fibrillarin Antibody
rRNA 2'-O-methyltransferase fibrillarin Antibody
Information: Target information shown above is from the UniProt Consortium.
Western blot analysis of extracts of K562 cells, using FBL antibody.
Please Note: All batches are extensively validated and are guaranteed to work as specified, however, QC data is not necessarily from the current lot on sale.
start icons start icons start icons start icons start icons (20)
Total Citations (102)
Description: Mouse monoclonal (38F3) antibody to Fibrillarin.
Application: WB, ICC/IF, IHC, IP
Host: Mouse
Isotype: IgG1
Immunogen: Yeast nuclear preparations.

£198 – £763

start icons start icons start icons start icons start icons (2)
Total Citations (11)
Description: Mouse monoclonal (38F3) antibody to Fibrillarin.
Application: WB, ICC/IF, IHC, IP
Host: Mouse
Isotype: IgG1
Immunogen: Yeast nuclear preparations.

£218 – £922

Description: Rabbit polyclonal antibody to FBL
Application: WB, IHC, IF
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein of human FBL.

£234

Description: Rabbit polyclonal antibody to FBL
Application: WB, IHC, IF, IP, RIP
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant full length Human FBL.

£220 – £366

Please Note: Anti-Fibrillarin Antibody is for research use only. It is not intended for diagnostic or therapeutic use.
Antibodies.com | A0158
Size Price Quantity
100µl £243
200µl £372

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Lead Time: Currently 4-6 Days
Shipping Information
  • £20 to United Kingdom
  • £35 to Europe