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Anti-Histone H3 (tri methyl K27) Antibody

Mouse monoclonal antibody to Histone H3 (tri methyl K27) from ABclonal (A10529).
Name: Anti-Histone H3 (tri methyl K27) Antibody
Description: Mouse monoclonal antibody to Histone H3 (tri methyl K27).
Applications: WB, IF
Dilutions: WB: 1:500 - 1:2000, IF: 1:50 - 1:100.
Reactivity: Human
Immunogen: A specific peptide of human TriMethyl-Histone H3-K27.
Host: Mouse
Clonality: Monoclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Affinity purification.
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Tissue Specificity: Expressed in testicular cells.
Sequence Similarities: Belongs to the histone H3 family.
Post-Translational Modification: Acetylation is generally linked to gene activation. Acetylation on Lys-10 (H3K9ac) impairs methylation at Arg-9 (H3R8me2s). Acetylation on Lys-19 (H3K18ac) and Lys-24 (H3K24ac) favors methylation at Arg-18 (H3R17me). Acetylation at Lys-123 (H3K122ac) by EP300/p300 plays a central role in chromatin structure: localizes at the surface of the histone octamer and stimulates transcription, possibly by promoting nucleosome instability (By similarity).
Cellular Location: Nucleus. Chromosome.
UniProt: Q16695
Gene ID: 8290
Synonyms: H3 histone family, member A Antibody
H3/A Antibody
H31_HUMAN Antibody
H3FA Antibody
Hist1h3a Antibody
HIST1H3B Antibody
HIST1H3C Antibody
HIST1H3D Antibody
HIST1H3E Antibody
HIST1H3F Antibody
HIST1H3G Antibody
HIST1H3H Antibody
HIST1H3I Antibody
HIST1H3J Antibody
histone 1, H3a Antibody
Histone cluster 1, H3a Antibody
Histone H3.1 Antibody
Histone H3/a Antibody
Histone H3/b Antibody
Histone H3/c Antibody
Histone H3/d Antibody
Histone H3/f Antibody
Histone H3/h Antibody
Histone H3/i Antibody
Histone H3/j Antibody
Histone H3/k Antibody
Histone H3/l Antibody
Information: Target information shown above is from the UniProt Consortium.
Total Citations (14)
Description: Rabbit polyclonal antibody to Histone H3 (K4)
Application: WB, IHC, IF
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide, corresponding to the N-terminal of Human Histone H3.

£165 – £283

Total Citations (13)
Description: Rabbit polyclonal antibody to Histone H3 (T22)
Application: WB, IHC
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide, corresponding to the N-terminal of Human Histone H3.

£165 – £283

Description: Rabbit polyclonal antibody to DiMethyl-Histone H3-K27.
Application: WB, IHC, IF, IP, ChIP, ChIPseq
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat

£199 – £452

Description: Rabbit polyclonal antibody to DiMethyl-Histone H3-K4.
Application: WB, IHC, IF, IP, ChIP, ChIPseq
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat

£199 – £452

Please Note: Anti-Histone H3 (tri methyl K27) Antibody is for research use only. It is not intended for diagnostic or therapeutic use.
Antibodies.com | A10529
Size Price Quantity
100µl £307
200µl £452

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