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Anti-Integrin α5 Antibody

Rabbit polyclonal antibody to Integrin α5 from ABclonal (A0832).
Name: Anti-Integrin α5 Antibody
Description: Rabbit polyclonal antibody to Integrin α5.
Applications: WB, IHC
Dilutions: WB: 1:500 - 1:1000, IHC: 1:50 - 1:100.
Reactivity: Human
Immunogen: A synthetic peptide of human ITGA5.
Protein Length: 1049
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Affinity purification.
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. ITGA5:ITGB1 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1 (PubMed:18635536, PubMed:25398877). ITGA5:ITGB1 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (PubMed:12807887, PubMed:17158881).
Sequence Similarities: Belongs to the integrin alpha chain family.
Post-Translational Modification: Proteolytic cleavage by PCSK5 mediates activation of the precursor.
Cellular Location: Membrane. Cell junction > Focal adhesion. Cell surface.
UniProt: P08648
Gene ID: 3678
Western blot analysis of extracts of various cell lines, using ITGA5 antibody.
Please Note: All batches are extensively validated and are guaranteed to work as specified, however, QC data is not necessarily from the current lot on sale.
Total Citations (1)
Description: Rabbit polyclonal antibody to Integrin α5 (F42)
Application: WB
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide, corresponding to amino acids 11-60 of Human Integrin α5.

£165 – £283

Description: Rabbit polyclonal antibody to Integrin α5 (LC)
Application: WB
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant full length Human Integrin α5.

£165 – £283

Please Note: Anti-Integrin α5 Antibody is for research use only. It is not intended for diagnostic or therapeutic use.
Antibodies.com | A0832
Size Price Quantity
100µl £243
200µl £372

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Lead Time: Currently 4-6 Days
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