Anti-Annexin A1 Anticorpo [ANXA1/3566] (A251997)

Nome
Anti-Annexin A1 Antibody [ANXA1/3566] - BSA and Azide free
Descrizione
Mouse monoclonal [ANXA1/3566] antibody to Annexin A1.
Specificità
The ANXA1 gene belongs to the annexin family, and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. ANXA1 promotes membrane fusion and is involved in exocytosis. The gene for ANXA1 is upregulated in hairy cell leukemia (HCL), and its protein expression is specific for HCL. Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance.
Applicazioni
Flow Cytometry, IF, WB, IHC-P
Diluizioni consigliate
Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, WB: 1-2 µg/ml, IHC-P: 1-2 µg/ml
Reattività
Human
Immunogeno
Recombinant full-length human Annexin A1 protein.
Specie ospite
Mouse
Clonalità
Monoclonal
Clona ID
ANXA1/3566
Isotipo
IgG2a
Catene leggere
kappa
Coniugare

Unconjugated

Purificazione
Protein A/G chromatography.
Concentrazione
1 mg/ml
Peso molecolare
38 kDa
Forma del prodotto
Liquid
Formulazione
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Conservazione
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Note generali
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-Annexin A1 Antibody [ANXA1/3566] (A248817).
Sinonimi
Annexin 1, Annexin I, Annexin I (lipocortin I), Annexin-1, AnnexinA1, AnnexinI, ANX 1, ANX A1, ANX1, ANXA 1, ANXA1, ANXA1 protein, ANXA1_HUMAN, Calpactin 2, Calpactin II, Calpactin-2, CalpactinII, Chromobindin 9, Chromobindin-9, Chromobindin9, HGNC:533, Lipocortin 1, Lipocortin I, Lipocortin1, LipocortinI, LPC 1, LPC1, p35, Phospholipase A2 inhibitory protein
Dichiarazione di non responsabilità
Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

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