Anti-BCL11A Anticorpo [PCRP-BCL11A-1G10] (A277750)

Anticorpo monoclonale [PCRP-BCL11A-1G10] di topo contro BCL11A per ELISA, WB, IP, Flow Cytometry e IF.

Alternative Formats and ConjugatesAlternative Formats

Spese di spedizione
Tempi di consegna
4-6 Giorni lavorativi
Telefono
+1 (314) 370-6046
Lun - Ven, 8:00 - 16:00 AST
E-mail
orders@antibodies.com
Nome
Anti-BCL11A Antibody [PCRP-BCL11A-1G10]
Descrizione
Mouse monoclonal [PCRP-BCL11A-1G10] antibody to BCL11A.
Specificità
Bcl-11a (CtIP-1, EVI9, B cell chronic lymphocytic leukemia (CLL)/lymphoma 11A) and Bcl-11b (CtIP-2, RIT1, B cell CLL/lymphoma 11B) genes play crucial roles in lymphopoiesis and influence the progression of hematopoietic malignancies. Disruption of the Bcl-11b locus is linked to T cell acute lymphoblastic leukemia, and the loss of heterozygosity in mice results in T cell lymphoma. Bcl-11 proteins are related C2H2 zinc-finger transcription factors that act as transcriptional repressors. Bcl-11b can interact with the metastasis-associated proteins MTA1 and MTA2 through the amino-terminal region. Bcl-11a is essential for postnatal development and normal lymphopoiesis. The Bcl-11a mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with Bcl-6.
Applicazioni
ELISA, WB, IP, Flow Cytometry, IF
Diluizioni consigliate
WB: 1-2 µg/ml, IP: 1-2µg / 100-500µg proteins, Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml
Reattività
Human
Reattività incrociata
This antibody is predicted to cross react with Mouse and Rat.
Immunogeno
Recombinant full-length human BCLL1A protein.
Specie ospite
Mouse
Clonalità
Monoclonal
Clona ID
PCRP-BCL11A-1G10
Isotipo
IgG2a
Coniugare

Unconjugated

Purificazione
Protein A/G chromatography.
Concentrazione
200 µg/ml
Peso molecolare
91.2 kDa
Forma del prodotto
Liquid
Formulazione
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Conservazione
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Note generali
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-BCL11A Antibody [PCRP-BCL11A-1G10] - BSA and Azide free (A278338).
Sinonimi
2810047E18Rik, B cell CLL/lymphoma 11A (zinc finger protein), B cell CLL/lymphoma 11A (zinc finger protein) isoform 2, B-cell CLL/lymphoma 11A, B-cell lymphoma/leukemia 11A, BC11A_HUMAN, BCL-11A, BCL11A B cell CLL/lymphoma 11A (zinc finger protein) isoform 1, BCL11A L, BCL11A S, BCL11A XL, BCL11a-M, BCL11AL, BCL11AS, BCL11AXL, C2H2 type zinc finger protein, COUP TF interacting protein 1, COUP-TF-interacting protein 1, Ctip1, CTIP1, mouse, homolog of, D930021L15Rik, Ecotropic viral integration site 9, Ecotropic viral integration site 9 homolog, Ecotropic viral integration site 9 protein, Ecotropic viral integration site 9 protein homolog, EVI-9, Evi9, Evi9, mouse, homolog of, FLJ10173, FLJ34997, HBFQTL5, KIAA1809, mKIAA1809, OTTHUMP00000159788, OTTHUMP00000159789, OTTHUMP00000201250, OTTHUMP00000202084, Zinc finger protein 856, ZNF856
Dichiarazione di non responsabilità
Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

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