Anti-CD137 Anticorpo (Biotin) (A282264)

Anti-CD137 Antibody (Biotin) - BSA and Azide free

Goat polyclonal antibody to CD137 (Biotin).

This antibody recognises human CD137, otherwise known as 4-1BB ligand receptor, a type I transmembrane glycoprotein and member of the tumour necrosis factor receptor superfamily, predominantly expressed by activated T cells, which acts as a receptor for 4-1BB ligand (4-1BBL).Interaction between CD137 and 4-1BBL, acts as a co-stimulatory signal for T cell activation and expansion, and is involved in the generation of cytotoxic T cells (Tc) and in the process of antigen presentation. CD137 also binds to the adaptor proteins TRAF1, 2 and 3 to act as a signal transducer of NF-kappaB activation.

WB, ELISA

ELISA: 0.5 - 2 µg/ml, WB: 0.1 - 0.2 µg/ml

Human

Recombinant human CD137.

Goat

Polyclonal

IgG

Biotin

Lyophilized

Reconstitute with 0.5 ml of sterile Phosphate Buffered Saline containing 0.1% Bovine Serum Albumin. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Gently mix after reconstitution. For long term storage the addition of 0.09% sodium azide is recommended.

Supplied in Phosphate Buffered Saline.

Lyophilized: Store at -20°C. Reconstituted: Store undiluted at -20°C, avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.

Goat anti Human CD137 antibody specifically recognizes human CD137, otherwise known as 4-1BB ligand receptor, a type I transmembrane glycoprotein and member of the tumour necrosis factor receptor superfamily, predominantly expressed by activated T cells, which acts as a receptor for 4-1BB ligand (4-1BBL).Interaction between CD137 and 4-1BBL, acts as a co-stimulatory signal for T cell activation and expansion, and is involved in the generation of cytotoxic T cells (Tc) and in the process of antigen presentation. CD137 also binds to the adaptor proteins TRAF1, 2 and 3 to act as a signal transducer of NF-kappaB activation.

4 1BB, 4 1BB ligand receptor, 4-1BB ligand receptor, 4-1BB Ligand Receptor T Cell, 4-1BB, mouse, homolog of, Antigen 4-1BB Homolog, CD 137, CD137 antigen, CDw137, HLDA VI, Homolog of mouse 4 1BB, ILA, Induced by lymphocyte activation, induced by lymphocyte activation (ILA), Interleukin activated receptor homolog of mouse Ly63, Ly63, mouse, homolog of, MGC2172, OTTHUMP00000044294, Receptor protein 4 1BB, T cell antigen 4 1BB homolog, T cell antigen ILA, T-cell antigen 4-1BB homolog, T-cell antigen ILA, TNF receptor superfamily member 9, TNFRSF9, TNR9_HUMAN, Tumor necrosis factor receptor superfamily member 9

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