Anti-CD161 Anticorpo [B199.2] (FITC) (A279745)

$420

Anticorpo monoclonale [B199.2] di topo contro CD161 (FITC) per Flow Cytometry.

Alternative Formats and ConjugatesAlternative Formats

Spese di spedizione
Tempi di consegna
4-6 Giorni lavorativi
Telefono
+1 (314) 370-6046
Lun - Ven, 8:00 - 16:00 AST
E-mail
orders@antibodies.com
Nome
Anti-CD161 Antibody [B199.2] (FITC)
Descrizione
Mouse monoclonal [B199.2] antibody to CD161 (FITC).
Specificità
This antibody recognises the human Killer cell lectin-like receptor subfamily B member 1, also known as CD161, C-type lectin domain family 5 member B, HNKR-P1a, NKR-P1A or Natural killer cell surface protein P1A. CD161 is a 225 amino acid ~25 kDa predicted molecular mass, single pass type II transmembrane glycoprotein with a single C-type lectin domain. CD161 is expressed by almost all NK cells and a subset of CD3+ve T cells (Lanier 1994).CD161, a member of the C-lectin is expressed as a disulphide bond-linked homodimeric cell surface protein, comprising two chains of ~40-44 kDa. CD161 acts as a receptor for another c-type lectin, LLT1 with roles in the regulation of NK cell and T cell function. recognises a similar epitope to the DX1 monoclonal antibody.
Applicazioni
Flow Cytometry
Diluizioni consigliate
Flow Cytometry: Nt - 1:10, Use 10µl of the suggested working dilution to label 106 cells in 100µl
Reattività
Human
Immunogeno
Purified human NK cells cultured in IL-2.
Specie ospite
Mouse
Clonalità
Monoclonal
Clona ID
B199.2
Isotipo
IgG1
Coniugare

FITC

Excitation: 490nm, Emission: 525nm

Purificazione
Protein A affinity chromatography of tissue culture supernatant.
Concentrazione
100 µg/ml
Forma del prodotto
Liquid
Formulazione
Supplied in Phosphate Buffered Saline with 1% BSA and 0.09% Sodium Azide.
Conservazione
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. This product is photosensitive and should be protected from light.
Note generali
Mouse anti Human CD161 antibody, clone B199.2 recognizes the human Killer cell lectin-like receptor subfamily B member 1, also known as CD161, C-type lectin domain family 5 member B, HNKR-P1a, NKR-P1A or Natural killer cell surface protein P1A. CD161 is a 225 amino acid ~25 kDa predicted molecular mass, single pass type II transmembrane glycoprotein with a single C-type lectin domain. CD161 is expressed by almost all NK cells and a subset of CD3+ve T cells (Lanier 1994).CD161, a member of the C-lectin is expressed as a disulphide bond-linked homodimeric cell surface protein, comprising two chains of ~40-44 kDa (Lanier et al. 1994). CD161 acts as a receptor for another c-type lectin, LLT1 with roles in the regulation of NK cell and T cell function (Aldemir et al. 2005).Mouse anti Human CD161 antibody, clone B199.2 cross-competes with and recognizes a similar epitope to the DX1 monoclonal antibody (Lanier et al. 1994).
Sinonimi
C-type lectin domain family 5 member B, CLEC5B, HNKR-P1a, Killer Cell Lectin like Receptor Subfamily B Member 1, Killer cell lectin-like receptor subfamily B member 1, KLRB1, KLRB1_HUMAN, Natural killer cell surface protein P1A, NKR, NKR P1, NKR-P1A, NKRP1, NKRP1A
Dichiarazione di non responsabilità
Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

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