This antibody recognizes a protein of 27kDa, identified as CLEC9A (C-type lectin domain family 9 member A). Its epitopes maps in aa 50-110. The C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily consists of a variety of proteins that share a common protein fold and have diverse functions, including cell-cell signaling, cell adhesion, glycoprotein turnover and immune responses. CLEC-9A, also known as DNGR1 (dendritic cell natural killer lectin group receptor 1), is a 241 amino acid single-pass type II membrane protein that contains one C-type lectin domain and belongs to the CTL/CTLD superfamily. Expressed in myeloid lineage cells, brain, spleen and thymus, CLEC-9A is a group V C-type lectin- like receptor (CTLR) that acts as an activation receptor.

Applicazioni

ELISA, Flow Cytometry, IF

Diluizioni consigliate

Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml

Reattività

Human

Immunogeno

RBL-2H3 cells expressing human DNGR-1 fused to an HA epitope.

Specie ospite

Mouse

Clonalità

Monoclonal

Clona ID

8F9

Isotipo

IgG2a

Catene leggere

kappa

Coniugare

Unconjugated

Purificazione

Protein A/G chromatography.

Concentrazione

200 µg/ml

Peso molecolare

27 kDa

Forma del prodotto

Liquid

Formulazione

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Conservazione

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Note generali

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-CLEC9A Antibody [8F9] - BSA and Azide free (A251934).

Sinonimi

C type lectin domain family 9, member A, C-type lectin domain family 9 member A, CD370, CLC9A_HUMAN, DNGR1, HEEE9341, PRO34046, UNQ9341

Controlli isotipo

Secondari adatti

Dichiarazione di non responsabilità

Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

Immagini (1)

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Figure 1: SDS-PAGE - Anti-CLEC9A Antibody [8F9] (A248754)

SDS-PAGE analysis of Anti-CLEC9A Antibody [8F9] under non-reduced and reduced conditions; showing intact IgG and intact heavy and light chains, respectively. SDS-PAGE analysis confirms the integrity and purity of the antibody.