Anti-Dopamine beta Hydroxylase Anticorpo [DBH/7222] (A316277)

$765

Anticorpo monoclonale [DBH/7222] di topo contro Dopamine beta Hydroxylase per IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Spese di spedizione
Tempi di consegna
4-6 Giorni lavorativi
Telefono
+1 (314) 370-6046
Lun - Ven, 8:00 - 16:00 AST
E-mail
orders@antibodies.com
Nome
Anti-Dopamine beta Hydroxylase Antibody [DBH/7222] - BSA and Azide free
Descrizione
Mouse monoclonal [DBH/7222] antibody to Dopamine beta Hydroxylase.
Specificità
Dopamine -hydroxylase (DBH) catalyzes the conversion of dopamine to noradrenaline in the biosynthesis of catecholamines. DBH is selectively expressed in noradrenergic and adrenergic neurons, as well as in neuroendocrine cells, and it serves as a specific protein marker for noradrenergic processes. The active form of DBH is a homotetramer, which is found in the lumen of synaptic vesicles of corresponding nerve cells, where it localizes to both the membrane and cytosol. DBH is induced by nerve growth factor and Insulin growth factor-1 and is regulated by intracellular second messengers protein kinase A, cyclic AMP, diacyl glycerol and Ca2+. Expression of DBH is transcriptionally mediated by Sp1, CREB and AP-1 proteins including c-Fos, c-Jun and JunD.
Applicazioni
IHC-P
Controllo positivo
Human adrenal gland or adrenal pheochromocytoma.
Diluizioni consigliate
IHC: 1-2 µg/ml
Reattività
Human
Immunogeno
Recombinant fragment (around Amino Acids 200-400) of human DBH protein. The exact sequence is proprietary.
Specie ospite
Mouse
Clonalità
Monoclonal
Clona ID
DBH/7222
Isotipo
IgG2
Catene leggere
kappa
Coniugare

Unconjugated

Purificazione
Protein A/G chromatography.
Concentrazione
1 mg/ml
Peso molecolare
78 kDa / 84 kDa
Forma del prodotto
Liquid
Formulazione
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Conservazione
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Sinonimi
dbh, DBM, Dopamine beta monooxygenase, Dopamine beta-hydroxylase (dopamine beta-monooxygenase), Dopamine beta-monooxygenase, DOPO_HUMAN, OTTHUMP00000022501, Soluble dopamine beta-hydroxylase
Dichiarazione di non responsabilità
Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

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