Anti-FOXL1 Anticorpo [PCRP-FOXL1-1F8] (A277605)

Anticorpo monoclonale [PCRP-FOXL1-1F8] di topo contro FOXL1 per IP, Flow Cytometry, IF, WB e IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Spese di spedizione
Tempi di consegna
4-6 Giorni lavorativi
Telefono
+1 (314) 370-6046
Lun - Ven, 8:00 - 16:00 AST
E-mail
orders@antibodies.com
Nome
Anti-FOXL1 Antibody [PCRP-FOXL1-1F8]
Descrizione
Mouse monoclonal [PCRP-FOXL1-1F8] antibody to FOXL1.
Specificità
FOXL1 is a 337 amino acid protein encoded by the mouse gene FOXL1. FOXL1 belongs to the forkhead family and contains one forkhead DNA-binding domain. The HNF3/forkhead family includes a large number of transcription factors that share a structurally related DNA binding domain. forkhead factors are known to play important roles both during development and in adults. FOXL1 is a winged helix transcriptional regulator expressed in the mesenchymal layer of developing and mature gastrointestinal tract. FOXL1-deficient mice exhibit various defects not only in the epithelial layer of the gastrointestinal tract but also in gut-associated lymphoid tissues. In the small intestine of FOXL1-deficient mice, the formation of Peyer's patches is affected, particularly in the caudal region. FOXL1 is a mesenchymal modifier of the Adenomatous Polyposis Coli (APC) gene products and plays a key role in gastrointestinal tumorigenesis.
Applicazioni
IP, Flow Cytometry, IF, WB, IHC-P
Diluizioni consigliate
IP: 1-2µg / 100-500µg proteins, Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, WB: 1-2 µg/ml, IHC-P: 1-2 µg/ml
Reattività
Human
Reattività incrociata
This antibody is predicted to cross react with Rat.
Immunogeno
Recombinant fragment, around amino acids 104-258, of human FOXL1 protein. The exact sequence is proprietary.
Specie ospite
Mouse
Clonalità
Monoclonal
Clona ID
PCRP-FOXL1-1F8
Isotipo
IgG1
Coniugare

Unconjugated

Purificazione
Protein A/G chromatography.
Concentrazione
200 µg/ml
Peso molecolare
36-41 kDa
Forma del prodotto
Liquid
Formulazione
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Conservazione
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Note generali
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-FOXL1 Antibody [PCRP-FOXL1-1F8] - BSA and Azide free (A278193).
Sinonimi
FKH 6, FKH6, FKHL 11, FKHL11, Forkhead (Drosophila) like 11, Forkhead box L1, Forkhead box protein L1, Forkhead related protein FKHL11, Forkhead related transcription factor 7, Forkhead-related protein FKHL11, Forkhead-related transcription factor 7, FOX L1, FOXL 1, FOXL1_HUMAN, FREAC 7, FREAC-7, FREAC7
Dichiarazione di non responsabilità
Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

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