Ricombinante Anti-HLA G Anticorpo [HLAG/8344R] (A315096)

$765

Anticorpo monoclonale [HLAG/8344R] di coniglio contro HLA G per IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Spese di spedizione
Tempi di consegna
4-6 Giorni lavorativi
Telefono
+1 (314) 370-6046
Lun - Ven, 8:00 - 16:00 AST
E-mail
orders@antibodies.com

Prodotti consigliati per Anti-HLA G Anticorpo

Nome
Anti-HLA G Antibody [HLAG/8344R]
Descrizione
Recombinant rabbit monoclonal [HLAG/8344R] antibody to HLA G.
Specificità
Major histocompatibility complex (MHC), human leukocyte antigen (HLA) molecules are cell-surface receptors that bind foreign peptides and present them to T lymphocytes. MHC class I molecules consist of two polypeptide chains, an a or heavy chain, and a non-covalently associated protein, 2-microglobulin. Cytotoxic T lymphocytes bind antigenic peptides presented by MHC class I molecules. Antigens that bind to MHC class I molecules are typically 8-10 residues in length and are stabilized in a peptide binding groove. MHC class II molecules are encoded by polymorphic MHC genes and consist of a noncovalent complex of an a and b chain. Helper T lymphocytes bind antigenic peptides presented by MHC class II molecules. MHC class II molecules bind 13-18 amino acid antigenic peptides. Accumulating in endosomal/lysosomal compartments and on the surface of B cells, HLA-DM and -DO molecules regulate binding of exogenous peptides to class II molecules (HLA-DR) by sustaining a conformation that favors peptide exchange. The differential structural properties of MHC class I and class II molecules account for their respective roles in activating different populations of T lymphocytes.
Applicazioni
IHC-P
Controllo positivo
Raji cells. Expressed in trophoblasts.
Diluizioni consigliate
IHC: 1-2 µg/ml
Reattività
Human
Immunogeno
Purified His-tagged HLA-G protein.
Specie ospite
Rabbit
Clonalità
Monoclonal
Clona ID
HLAG/8344R
Isotipo
IgG
Catene leggere
kappa
Coniugare

Unconjugated

Purificazione
Protein A/G chromatography.
Concentrazione
200 µg/ml
Peso molecolare
39 kDa
Forma del prodotto
Liquid
Formulazione
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Conservazione
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Sinonimi
B2 microglobulin, DADB-15K14.8, HLA 6.0, HLA class I histocompatibility antigen alpha chain G, HLA class I histocompatibility antigen, alpha chain G, HLA class I molecule, HLA G antigen, HLA G histocompatibility antigen class I G, HLA G3, HLA-G, HLA-G histocompatibility antigen, class I, HLA60, HLAG, HLAG_HUMAN, Major histocompatibility complex class I G, MHC class I antigen, MHC class I antigen G, MHC G, T-cell A locus, TCA
Dichiarazione di non responsabilità
Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

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