Anti-ICAM1 Anticorpo [1A29] (A279070)

Anti-ICAM1 Antibody [1A29] - BSA and Azide free

Mouse monoclonal [1A29] antibody to ICAM1.

This antibody recognises the rat CD54 cell surface antigen, also known as intercellular adhesion molecule-1 (ICAM-1), a ~90 kDa adhesion molecule belonging to the immunoglobulin superfamily.CD54 is a cell surface ligand of the lymphocyte integrin, LFA-1 and plays an important role in various cell-cell interactions in the immune system. Cross-linking of ICAM-1 using clone 1A29 induces calcium signaling. Mouse anti Rat CD54 antibody, clone 1A29 inhibits homotypic aggregation of cells including PHA blasts.

Flow Cytometry, IF, IHC-Fr, IP, WB, IHC-P, Functional Assays

Flow Cytometry: 1:25 - 1:50, Use 10µl of the suggested working dilution to label 10⁶ cells in 100µl.

Rat

Rat Ax cells (a HEV derived cell line).

Mouse

Monoclonal

1A29

IgG1

Unconjugated

1 mg/ml

Liquid

Supplied in Phosphate Buffered Saline.

Store undiluted at -20°C only. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.

Mouse anti Rat CD54 antibody, clone 1A29 recognizes the rat CD54 cell surface antigen, also known as intercellular adhesion molecule-1 (ICAM-1), a ~90 kDa adhesion molecule belonging to the immunoglobulin superfamily.CD54 is a cell surface ligand of the lymphocyte integrin, LFA-1 and plays an important role in various cell-cell interactions in the immune system. Cross-linking of ICAM-1 using clone 1A29 induces calcium signaling (Etienne et al. 1998).Mouse anti Rat CD54 antibody, clone 1A29 inhibits homotypic aggregation of cells including PHA blasts (Tamatani & Miyasaka 1990).

Antigen identified by monoclonal, BB 2, BB2, CD 54 , CD54, CD54 antigen , CD_antigen=CD54, Cell surface glycoprotein P3.58 , Human rhinovirus receptor , ICAM 1, ICAM-1, ICAM1_HUMAN, Intercellular adhesion molecule 1 , intercellular adhesion molecule 1 (CD54), human rhinovirus receptor, Major group rhinovirus receptor , MALA 2, MALA2 , MGC6195, MyD 10, MyD10, P3.58 , Surface antigen of activated B cells , Surface antigen of activated B cells, BB2