Anti-ICOS Ligand Anticorpo [ICOSL/3111] (A251758)

Anticorpo monoclonale [ICOSL/3111] di topo contro ICOS Ligand per ELISA, Flow Cytometry, IF e IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Spese di spedizione
Tempi di consegna
4-6 Giorni lavorativi
Telefono
+1 (314) 370-6046
Lun - Ven, 8:00 - 16:00 AST
E-mail
orders@antibodies.com
Nome
Anti-ICOS Ligand Antibody [ICOSL/3111] - BSA and Azide free
Descrizione
Mouse monoclonal [ICOSL/3111] antibody to ICOS Ligand.
Specificità
This antibody recognizes a protein of 36kDa, identified as ICOS-L. It is a ligand for the ICOS receptor that initiates T and B cell proliferation and cytokine secretion. ICOS-L interactions play an essential role in T cell-dependent B cell activation in peripheral lymphoid organs such as spleen and lymph nodes. ICOS-L protein is present in myeloid leukocytes, and by Northern blot there are 2.4, 3.0, and 7.0 kb transcripts in brain, heart, kidney, and liver, with lower expression in colon and thymus, and a 1.1 kb transcript in leukocytes. Tumor necrosis factor alpha (TNF), granulocyte-macrophage colony-stimulating factor (GM-CSF) and interleukin-4 (IL-4) enhance its expression. LPS-induced up-regulation of ICOS-L is dependent on the MyD88-dependent signaling pathway.
Applicazioni
ELISA, Flow Cytometry, IF, IHC-P
Diluizioni consigliate
Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, IHC-P: 1-2 µg/ml
Reattività
Human
Immunogeno
Recombinant fragment, around amino acids 23-149, of human ICOSLG protein. The exact sequence is proprietary.
Specie ospite
Mouse
Clonalità
Monoclonal
Clona ID
ICOSL/3111
Isotipo
IgG1
Catene leggere
kappa
Coniugare

Unconjugated

Purificazione
Protein A/G chromatography.
Concentrazione
1 mg/ml
Peso molecolare
36 kDa
Forma del prodotto
Liquid
Formulazione
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Conservazione
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Note generali
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-ICOS Ligand Antibody [ICOSL/3111] (A248576).
Sinonimi
B7 H2, B7 homolog 2, B7 homologue 2, B7 like protein Gl50, B7 related protein 1, B7-H2, B7-like protein Gl50, B7-related protein 1, B7H2, B7RP 1, B7RP-1, B7RP1, CD 275, CD275, CD275 antigen, GL 50, GL50, ICOS L, ICOS LG, ICOSL, Icoslg, ICOSL_HUMAN, Inducible T cell co stimulator ligand, KIAA0653, LICOS, Transmembrane protein B7 H2 ICOS ligand
Dichiarazione di non responsabilità
Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

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