Ricombinante Anti-IMP3 Anticorpo [IMP3/8934R] (A315183)

Anti-IMP3 Antibody [IMP3/8934R]

Recombinant rabbit monoclonal [IMP3/8934R] antibody to IMP3.

Imp3, also known as BRMS2, C15orf12 or MRPS4, is a 184 amino acid protein that contains one S4 RNA-binding domain and is the mammalian homolog of the yeast Imp3 protein. Localized to the nucleus, Imp3 exists as a component of a heterotrimeric complex consisting of MPP10, Imp3 and Imp4 and, in this complex, plays a key role in early cleavage events during pre-18S ribosomal processing. The gene encoding Imp3 maps to human chromosome 15, which houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes.

IHC-P

Human liver, brain or lung.

IHC: 1-2 µg/ml

Human

Recombinant fragment of human IMP3 protein. The exact sequence is proprietary.

Rabbit

Monoclonal

IMP3/8934R

IgG

kappa

Protein A/G chromatography.

200 µg/ml

22 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

BRMS2, C15orf12, Cancer/testis antigen 98, Chromosome 15 open reading frame 12, CT98, DKFZp586L0118, DKFZp686F1078, FLJ10968, hKOC, IF2B3_HUMAN, IGF II mRNA binding protein 3, IGF-II mRNA-binding protein 3, IGF2 mRNA binding protein 3, IGF2 mRNA-binding protein 3, IGF2BP3, IMP 3, IMP-3, IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast), IMP3_HUMAN, Insulin like growth factor 2 mRNA binding protein 3, Insulin-like growth factor 2 mRNA-binding protein 3, KH domain containing protein overexpressed in cancer, KH domain-containing protein overexpressed in cancer, KOC 1, KOC1, Mitochondrial ribosomal protein S4, MRPS4, OTTHUMP00000183524, U3 small nucleolar ribonucleoprotein protein imp3, U3 snoRNP protein 3 homolog, U3 snoRNP protein imp3, VICKZ 3, VICKZ family member 3, VICKZ3