Anti-Integrin beta 3 Anticorpo [HM beta 3.1] (PE) (A280611)

$515

Anticorpo monoclonale [HM beta 3.1] di criceto contro Integrin beta 3 (PE) per Flow Cytometry.

Alternative Formats and ConjugatesAlternative Formats

Spese di spedizione
Tempi di consegna
4-6 Giorni lavorativi
Telefono
+1 (314) 370-6046
Lun - Ven, 8:00 - 16:00 AST
E-mail
orders@antibodies.com
Nome
Anti-Integrin beta 3 Antibody [HM beta 3.1] (PE)
Descrizione
Hamster monoclonal [HM beta 3.1] antibody to Integrin beta 3 (PE).
Specificità
This antibody recognises the murine integrin beta 3 subunit (CD61), a ~90 kDa a type I membrane protein, expressed primarily on megakaryocytes, platelets, monocytes, macrophages, granulocytes and endothelial cells. CD61 associates with either the alpha IIb integrin (CD41) or the alpha V integrin (CD51) to form the platelet glycoprotein complex IIb/IIIa and the vitronectin receptor (VNR) respectively. The heterodimers formed with CD61 are receptor for a variety of ligands including fibrinogen, fibronectin, von Willebrands factor (vWF), vitronectin and thrombospondin.Hamster anti Mouse CD61 antibody, clone HM beta 3-1 is reported to partially inhibit the binding of CD61 to fibronectin.
Applicazioni
Flow Cytometry
Diluizioni consigliate
Flow Cytometry: Neat - 1:10, Use 10µl of the suggested working dilution to label 106 cells in 100µl. The Fc region of monoclonal antibodies may bind to cells expressing low affinity Fc receptors. This may be reduced by using SeroBlock FcR (BUF041A/BUF041B).
Reattività
Mouse, Rat
Immunogeno
Mouse alpha 5 beta 3 protein purified from the mouse hybridoma 2B4.
Specie ospite
Hamster
Clonalità
Monoclonal
Clona ID
HM beta 3.1
Isotipo
IgG
Coniugare

PE

Excitation: 565nm, Emission: 578nm

Purificazione
Protein G affinity chromatography of tissue culture supernatant.
Concentrazione
Reconstitution dependent.
Forma del prodotto
Lyophilized
Ricostituzione
Reconstitute with 1 ml of distilled water.
Formulazione
Supplied in Phosphate Buffered Saline with 1% BSA, 5% Sucrose, and 0.09% Sodium Azide.
Conservazione
Store undiluted at 4°C. Do not freeze! This product is photosensitive and should be protected from light.
Note generali
Hamster anti Mouse CD61 antibody, clone HM beta 3-1 recognizes the murine integrin beta 3 subunit (CD61), a ~90 kDa a type I membrane protein, expressed primarily on megakaryocytes, platelets, monocytes, macrophages, granulocytes and endothelial cells. CD61 associates with either the alpha IIb integrin (CD41) or the alpha V integrin (CD51) to form the platelet glycoprotein complex IIb/IIIa and the vitronectin receptor (VNR) respectively. The heterodimers formed with CD61 are receptor for a variety of ligands including fibrinogen, fibronectin, von Willebrands factor (vWF), vitronectin and thrombospondin.Hamster anti Mouse CD61 antibody, clone HM beta 3-1 is reported to partially inhibit the binding of CD61 to fibronectin (Yasuda et al. 1995).
Sinonimi
BDPLT16, BDPLT2, CD 61, CD61, CD61 antigen, GP3A, GPIIIa, GT, HPA 1, HPA 4, Integrin beta 3 (platelet glycoprotein IIIa antigen CD61), Integrin beta chain beta 3, Integrin beta-3, ITB3_HUMAN, ITG B3, ITGB 3, ITGB3, NAIT, Platelet fibrinogen receptor beta subunit, Platelet fibrinogen receptor, beta subunit, Platelet glycoprotein IIIa, Platelet glycoprotein IIIa precursor, Platelet membrane glycoprotein IIIa, PTP
Dichiarazione di non responsabilità
Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

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