This antibody recognises human interferon beta (IFN Beta), a ~22 kDa cytokine with wide-ranging antiviral, antimicrobial and antitumor effects. Interferons also serve to activate macrophages, natural killer cells and the presentation of antigens to the immune system by the major histocompatibility complex. The production of interferon is induced in response to microbes and other cytokines. The interferons are widely used to treat a variety of diseases and IFNB in particular is used to treat relapsing-remitting multiple sclerosis. recognises glycosylated and non-glycosylated human IFNß and there is no cross-reactivity with human interferon alpha or human interferon gamma.

Applicazioni

WB, ELISA

Reattività

Human

Immunogeno

Recombinant full length human IFN Beta, expressed in E.coli.

Specie ospite

Mouse

Clonalità

Monoclonal

Clona ID

BB4

Isotipo

IgG2a

Coniugare

Unconjugated

Purificazione

Protein G affinity chromatography of tissue culture supernatant.

Concentrazione

1 mg/ml

Forma del prodotto

Liquid

Formulazione

Supplied in Phosphate Buffered Saline with <0.1% Sodium Azide.

Conservazione

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Note generali

Mouse anti Human IFN beta antibody, clone BB4 recognizes human interferon beta (IFN Beta), a ~22 kDa cytokine with wide-ranging antiviral, antimicrobial and antitumor effects. Interferons also serve to activate macrophages, natural killer cells and the presentation of antigens to the immune system by the major histocompatibility complex. The production of interferon is induced in response to microbes and other cytokines. The interferons are widely used to treat a variety of diseases and IFNB in particular is used to treat relapsing-remitting multiple sclerosis. Mouse anti Human IFN beta antibody, clone BB4 recognizes glycosylated and non-glycosylated human IFNß and there is no cross-reactivity with human interferon alpha or human interferon gamma.

Sinonimi

beta-interferon, Fibroblast interferon, IFB, IFF, IFN beta, IFN-beta, IFNB, IFNB 1, IFNB1, IFNB_HUMAN, Interferon beta 1 fibroblast, Interferon beta precursor, MGC96956

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Secondari adatti

Dichiarazione di non responsabilità

Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.