Ricombinante Anti-MMP3 Anticorpo [MMP3/1994R] (A249372)

Anticorpo monoclonale [MMP3/1994R] di coniglio contro MMP3 per ELISA, Flow Cytometry e WB.

Alternative Formats and ConjugatesAlternative Formats

Spese di spedizione
Tempi di consegna
4-6 Giorni lavorativi
Telefono
+1 (314) 370-6046
Lun - Ven, 8:00 - 16:00 AST
E-mail
orders@antibodies.com
Nome
Anti-MMP3 Antibody [MMP3/1994R]
Descrizione
Recombinant rabbit monoclonal [MMP3/1994R] antibody to MMP3.
Specificità
The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-3, MMP-10 and MMP-11 (also designated stromelysin-1, 2 and 3, respectively) activate procollagenase. MMP-3 activation of procollagenase can occur via two pathways. Direct activation by MMP-3 is slow and activation by MMP-3 in conjunction with tissue or plasma proteinases is rapid. MMP-10 is expressed in small intestine, and at lower levels in lung and heart. MMP-11 is specifically expressed in stromal cells of breast carcinomas and contributes to epithelial cell malignancies.
Applicazioni
ELISA, Flow Cytometry, WB
Diluizioni consigliate
Flow Cytometry: 1-2 µg/million cells, WB: 1-2 µg/ml
Reattività
Human
Immunogeno
Recombinant fragment, around amino acids 317-327, of human MMP3 protein. The exact sequence is proprietary.
Specie ospite
Rabbit
Clonalità
Monoclonal
Clona ID
MMP3/1994R
Isotipo
IgG
Coniugare

Unconjugated

Purificazione
Protein A chromatography.
Concentrazione
200 µg/ml
Peso molecolare
57 kDa
Forma del prodotto
Liquid
Formulazione
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Conservazione
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Note generali
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-MMP3 Antibody [MMP3/1994R] - BSA and Azide free (A252552).
Sinonimi
CHDS6, Matrix metalloproteinase 3, Matrix metalloproteinase-3, MGC126102, MGC126103, MGC126104, MMP 3, MMP-3, MMP3_HUMAN, Proteoglycanase , SL-1, SL1 , STMY, STMY1, STR1, Stromelysin 1, Stromelysin-1, Transin 1, Transin-1
Dichiarazione di non responsabilità
Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

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