Anti-MX1 Anticorpo [MX1/7527] (A315347)

$765

Anticorpo monoclonale [MX1/7527] di topo contro MX1 per IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Spese di spedizione
Tempi di consegna
4-6 Giorni lavorativi
Telefono
+1 (314) 370-6046
Lun - Ven, 8:00 - 16:00 AST
E-mail
orders@antibodies.com
Nome
Anti-MX1 Antibody [MX1/7527]
Descrizione
Mouse monoclonal [MX1/7527] antibody to MX1.
Specificità
The Dynamin family of microtubule-associated proteins function as GTPases that are involved in microtubule bundling and endocytosis. In mice, Mx2 (myxovirus resistance protein 2) and Mx1 (myxovirus resistance protein 1) are members of the Dynamin family that are involved in the immune response to viral infections. Localized to the cytoplasm, Mx2 contains one GED domain and is expressed in response to viral infection or treatment by IFN-a/IFN-b. Once expression is induced, Mx2 accumulates in the cytoplasm and inhibits the replication of vesicular stomatitis virus (VSV), thereby conferring resistance to VSV infection. Unlike Mx2, Mx1 is localized to the nucleus where, upon induction by IFN-a/IFN-b, it provides selective resistance to infection by the highly lethal H5N1 influenza virus. In humans, MxA and MxB function in a similar manner to Mx1 and Mx2, conferring resistance to specific target viruses. Mx3 is a rat-specific member of the myxovirus resistance protein family.
Applicazioni
IHC-P
Controllo positivo
Human spleen, tonsil, breast cancer or colon cancer tissues.
Diluizioni consigliate
IHC: 1-2 µg/ml
Reattività
Human
Immunogeno
Recombinant fragment (around Amino Acids 400-592) of human MX1 protein. The exact sequence is proprietary.
Specie ospite
Mouse
Clonalità
Monoclonal
Clona ID
MX1/7527
Isotipo
IgG2
Catene leggere
kappa
Coniugare

Unconjugated

Purificazione
Protein A/G chromatography.
Concentrazione
200 µg/ml
Peso molecolare
72 kDa
Forma del prodotto
Liquid
Formulazione
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Conservazione
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Sinonimi
Human interferon regulated resistance GTP binding protein MXA, IFI 78, IFI 78K, IFI-78K, IFI78, IFI78K, Interferon induced GTP binding protein Mx1, Interferon induced protein p78, Interferon inducible protein p78, Interferon regulated resistance GTP binding protein, Interferon regulated resistance GTP binding protein MxA, Interferon-induced GTP-binding protein Mx1, Interferon-induced protein p78, Interferon-regulated resistance GTP-binding protein MxA, MX, MX 1, MX dynamin-like GTPase 1, MX1_HUMAN, MxA, Myxoma resistance protein 1, Myxovirus (influenza virus) resistance 1 interferon inducible, Myxovirus (influenza virus) resistance 1 interferon inducible protein p78, Myxovirus (influenza) resistance 1 homolog of murine, Myxovirus resistance 1, mouse, homolog of, Myxovirus resistance protein 1, N-terminally processed
Dichiarazione di non responsabilità
Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

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