Anti-PKC iota Anticorpo [PRKCI/4911] (A277763)

Anticorpo monoclonale [PRKCI/4911] di topo contro PKC iota per IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Spese di spedizione
Tempi di consegna
4-6 Giorni lavorativi
Telefono
+1 (314) 370-6046
Lun - Ven, 8:00 - 16:00 AST
E-mail
orders@antibodies.com
Nome
Anti-PKC iota Antibody [PRKCI/4911]
Descrizione
Mouse monoclonal [PRKCI/4911] antibody to PKC iota.
Specificità
Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions, including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into at least two major classes, including conventional (c) PKC isoforms (α, βI, βII and γ) and novel (n) PKC isoforms ( L, , Ã·, , , l/i, m and n). Patterns of expression for each PKC isoform differ among tissues and PKC family members exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of PKC L and are independent of Ca2+. On the other hand, most of the other PKC members possess phorbol ester-binding activities and kinase activities.
Applicazioni
IHC-P
Diluizioni consigliate
IHC-P: 1-2 µg/ml
Reattività
Human, Feline, Canine
Immunogeno
Recombinant fragment, around amino acids 100-300, of human PKC iota. The exact sequence is proprietary.
Specie ospite
Mouse
Clonalità
Monoclonal
Clona ID
PRKCI/4911
Isotipo
IgG2b
Catene leggere
kappa
Coniugare

Unconjugated

Purificazione
Protein A/G chromatography.
Concentrazione
200 µg/ml
Peso molecolare
68 kDa
Forma del prodotto
Liquid
Formulazione
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Conservazione
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Note generali
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-PKC iota Antibody [PRKCI/4911] - BSA and Azide free (A278351).
Sinonimi
aPKC lambda/iota, aPKC-lambda/iota, Atypical protein kinase C lambda/iota, Atypical protein kinase C-lambda/iota, DXS1179E, KPCI_HUMAN, MGC26534, nPKC iota, nPKC-iota, nPKCiota, PKC lambda, PKC lambda/iota, PKCI, PKCiota, PKClambda, PRKC iota, PRKC lambda/iota, PRKC-lambda/iota, PRKCI, Protein kinase C iota, Protein kinase C iota type
Dichiarazione di non responsabilità
Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

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