Ricombinante Anti-Podoplanin / gp36 Anticorpo [PDPN/7808R] (A315523)

Anti-Podoplanin / gp36 Antibody [PDPN/7808R]

Recombinant rabbit monoclonal [PDPN/7808R] antibody to Podoplanin / gp36.

It recognizes a muco-protein of 38-43kDa, which is identified as Podoplanin (PDPN). It localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes. It is selectively expressed in lymphatic endotheliumand in a subset of angiosarcomas with probable lymphatic differentiation. Recent studies have also shown podoplanin to be a highly sensitive and relatively specific marker for epithelioid mesothelioma. Therefore, it can be used in a panel to distinguish mesotheliomas or mesothelial cells from pulmonary carcinomas.

ELISA, IF, IHC-P

Human tonsil, cervical or lung carcinoma tissues.

IF: 1-2 µg/ml, IHC: 1-2 µg/ml

Human

Recombinant fragment (around Amino Acids 1-100) of human PDPN protein. The exact sequence is proprietary.

Rabbit

Monoclonal

PDPN/7808R

IgG

Unconjugated

Protein A/G chromatography.

200 µg/ml

17 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Aggrus, Glycoprotein 36, Glycoprotein 36 KD, gp 36, GP 38, GP 40, gp36, GP38, GP40, HT1A 1, HT1A1, hT1alpha 1, hT1alpha 2, hT1alpha1, hT1alpha2, Lung type I cell membrane associated glycoprotein, Lung type I cell membrane associated glycoprotein isoform a, Lung type I cell membrane associated glycoprotein T1A 2, OTS 8, OTS8, OTTHUMP00000009640, OTTHUMP00000044504, PA2.26, PA2.26 antigen, Pdpn, PDPN_HUMAN, Podoplanin, PSEC0003, PSEC0025, T1 alpha, T1 ALPHA GENE, T1-alpha, T1A, T1A 2, TI1A, TIA 2, TIA2