Nestin è un gene codificato dal simbolo NES. È noto anche come NES. Nestin ha una massa di 177.44kDa e una lunghezza di amminoacidi di 1621.
Offriamo 7 Nestin ELISA kit per il rilevamento qualitativo o quantitativo di Nestin da campioni di Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
Required for brain and eye development. Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells (By similarity).
Sommario di Entrez
This gene encodes a member of the intermediate filament protein family and is expressed primarily in nerve cells.
Specificità del tessuto
CNS stem cells.
Somiglianze di sequenza
Belongs to the intermediate filament family.
Modifica post-translazionale
Constitutively phosphorylated. This increases during mitosis when the cytoplasmic intermediate filament network is reorganized (By similarity).
