ACT è un gene codificato dal simbolo FHL5. Altri nomi includono: Four and a half LIM domains protein 5; FHL-5ivator of cAMP-responsive element modulator in testisivator of CREM in testis; FHL5. ACT ha una massa di 32.72kDa e una lunghezza di amminoacidi di 284.
Offriamo 2 anticorpi contro ACT, allevati nel Coniglio e Topo, che sono adatti per WB e ELISA con campioni derivati da Umano e Topo.
Informazioni su geni e proteine
Riepilogo UniProt
May be involved in the regulation of spermatogenesis. Stimulates CREM transcriptional activity in a phosphorylation-independent manner.
Sommario di Entrez
The protein encoded by this gene is coordinately expressed with activator of cAMP-responsive element modulator (CREM). It is associated with CREM and confers a powerful transcriptional activation function. CREM acts as a transcription factor essential for the differentiation of spermatids into mature spermatozoa. There are multiple polyadenylation sites found in this gene. Polymorphisms in this gene may be associated with susceptibility for migraine headaches. Alternative splicing results in multiple transcript variants encoding the same protein.
Specificità del tessuto
Testis-specific (at protein level).
Posizione cellulare
Nucleus.
Nuclei of round and elongated spermatids.
