Claudin 2 è un gene codificato dal simbolo CLDN2. Altri nomi includono: Claudin-2; SP82; CLDN2. Claudin 2 ha una massa di 24.55kDa e una lunghezza di amminoacidi di 230.
Offriamo 7 anticorpi contro Claudin 2, allevati nel Coniglio, che sono adatti per WB, IHC, ELISA e ICC/IF con campioni derivati da Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
Sommario di Entrez
This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene.
Somiglianze di sequenza
Belongs to the claudin family.
Modifica post-translazionale
The disulfide bond is necessary for pore formation, but is not required for correct protein trafficking.
Posizione cellulare
Cell junction > Tight junction. Cell membrane.