CNTN4 è un gene codificato dal simbolo CNTN4. Altri nomi includono: Contactin-4; Brain-derived immunoglobulin superfamily protein 2; BIG-2. CNTN4 ha una massa di 113.45kDa e una lunghezza di amminoacidi di 1026.
Offriamo 4 anticorpi contro CNTN4, allevati nel Coniglio e Capra, che sono adatti per WB, ELISA e ICC/IF con campioni derivati da Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity. May be involved in synaptogenesis.
Sommario di Entrez
This gene encodes a member of the contactin family of immunoglobulins. Contactins are axon-associated cell adhesion molecules that function in neuronal network formation and plasticity. The encoded protein is a glycosylphosphatidylinositol-anchored neuronal membrane protein that may play a role in the formation of axon connections in the developing nervous system. Deletion or mutation of this gene may play a role in 3p deletion syndrome and autism spectrum disorders. Alternative splicing results in multiple transcript variants.
Specificità del tessuto
Mainly expressed in brain. Highly expressed in cerebellum and weakly expressed in corpus callosum, caudate nucleus, amygdala and spinal cord. Also expressed in testis, pancreas, thyroid, uterus, small intestine and kidney. Not expressed in skeletal muscle. Isoform 2 is weakly expressed in cerebral cortex.
Somiglianze di sequenza
Belongs to the immunoglobulin superfamily. Contactin family.
Posizione cellulare
Cell membrane. Secreted.
