CTBP2 è un gene codificato dal simbolo CTBP2. È noto anche come C-terminal-binding protein 2. CTBP2 ha una massa di 48.95kDa e una lunghezza di amminoacidi di 445.
Offriamo 14 anticorpi contro CTBP2, allevati nel Coniglio e Topo, che sono adatti per WB, IHC, ELISA, ICC/IF, Citometria a Flusso e IP con campioni derivati da Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation (By similarity).
Sommario di Entrez
This gene produces alternative transcripts encoding two distinct proteins. One protein is a transcriptional repressor, while the other isoform is a major component of specialized synapses known as synaptic ribbons. Both proteins contain a NAD+ binding domain similar to NAD+-dependent 2-hydroxyacid dehydrogenases. A portion of the 3' untranslated region was used to map this gene to chromosome 21q21.3; however, it was noted that similar loci elsewhere in the genome are likely. Blast analysis shows that this gene is present on chromosome 10. Several transcript variants encoding two different isoforms have been found for this gene.
Specificità del tessuto
Ubiquitous. Highest levels in heart, skeletal muscle, and pancreas.
Somiglianze di sequenza
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
Posizione cellulare
Nucleus. Cell junction > Synapse.
