Histone H1 è un gene codificato dal simbolo H1-0. Comunemente indicato anche come: Histone H1.0'(0); H1-0; H1F0; H1FV. Histone H1 ha una massa di 20.86kDa e una lunghezza di amminoacidi di 194.
Offriamo 32 anticorpi contro Histone H1, allevati nel Coniglio e Topo, che sono adatti per WB, IHC, ELISA, ICC/IF, Citometria a Flusso e IP con campioni derivati da Umano, Topo, Ratto e Scimmia.
Informazioni su geni e proteine
Riepilogo UniProt
Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures. The histones H1.0 are found in cells that are in terminal stages of differentiation or that have low rates of cell division.
Sommario di Entrez
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. The protein encoded is a replication-independent histone that is a member of the histone H1 family. This gene contains introns, unlike most histone genes. The related mouse gene is expressed only in oocytes.
Somiglianze di sequenza
Belongs to the histone H1/H5 family.
Modifica post-translazionale
Phosphorylated on Ser-17 in RNA edited version.
Posizione cellulare
Nucleus. Chromosome.
The RNA edited version has been localized to nuclear speckles. During mitosis, it appears in the vicinity of condensed chromosomes.
