ITGA11 è un gene codificato dal simbolo ITGA11. È noto anche come Integrin alpha-11. ITGA11 ha una massa di 133.47kDa e una lunghezza di amminoacidi di 1188.
Offriamo 3 anticorpi contro ITGA11, allevati nel Coniglio e Capra, che sono adatti per WB, IHC e ELISA con campioni derivati da Umano e Topo.
Informazioni su geni e proteine
Riepilogo UniProt
Integrin alpha-11/beta-1 is a receptor for collagen.
Sommario di Entrez
This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein contains an I domain, is expressed in muscle tissue, dimerizes with beta 1 integrin in vitro, and appears to bind collagen in this form. Therefore, the protein may be involved in attaching muscle tissue to the extracellular matrix. Alternative transcriptional splice variants have been found for this gene, but their biological validity is not determined.
Specificità del tessuto
According to PubMed:10464311, highest levels of expression in uterus and heart, intermediate levels in skeletal muscle and intermediate to low levels in pancreas, kidney and placenta. According to PubMed:10486209, also found in brain, colon, lung, small intestine, stomach, testis, salivary glands, thyroid glands and prostate. Very low levels in peripheral blood lymphocytes, fetal brain and fetal liver.
Somiglianze di sequenza
Belongs to the integrin alpha chain family.
Posizione cellulare
Membrane.
