L3MBTL3 è un gene codificato dal simbolo L3MBTL3. Comunemente indicato anche come: Lethal(3)malignant brain tumor-like protein 3; H-l(3)mbt-like protein 3; MBT-1; KIAA1798; MBT1. L3MBTL3 ha una massa di 88.34kDa e una lunghezza di amminoacidi di 780.
Offriamo 2 anticorpi contro L3MBTL3, allevati nel Coniglio, che sono adatti per WB, IHC, ICC/IF e IP con campioni derivati da Umano e Topo.
Informazioni su geni e proteine
Riepilogo UniProt
Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Required for normal maturation of myeloid progenitor cells (By similarity).
Sommario di Entrez
This gene encodes a member of the malignant brain tumor (MBT) family of chromatin interacting transcriptional repressors. Members of this family function as methyl-lysine readers, which recognize methylated lysine residues on histone protein tails, and are associated with the repression of gene expression. The encoded protein may regulate hematopoiesis. Homozygous deletion of this gene has been observed in human patients with medulloblastoma.
Posizione cellulare
Nucleus.
