Neuron navigator 1 è un gene codificato dal simbolo NAV1. Comunemente indicato anche come: Pore membrane and/or filament-interacting-like protein 3; Steerin-1; Unc-53 homolog 1; unc53H1; NAV1; KIAA1151; KIAA1213; POMFIL3; STEERIN1. Neuron navigator 1 ha una massa di 202.47kDa e una lunghezza di amminoacidi di 1877.
Offriamo 4 anticorpi contro Neuron navigator 1, allevati nel Ratto, che sono adatti per WB e ICC/IF con campioni derivati da Umano.
Informazioni su geni e proteine
Riepilogo UniProt
May be involved in neuronal migration.
Sommario di Entrez
This gene belongs to the neuron navigator family and is expressed predominantly in the nervous system. The encoded protein contains coiled-coil domains and a conserved AAA domain characteristic for ATPases associated with a variety of cellular activities. This gene is similar to unc-53, a Caenorhabditis elegans gene involved in axon guidance. The exact function of this gene is not known, but it is thought to play a role in in neuronal development and regeneration. Alternative splicing results in multiple transcript variants.
Specificità del tessuto
Broadly expressed at low levels. Expressed at high levels in heart, skeletal muscle and placenta.
Somiglianze di sequenza
Belongs to the Nav/unc-53 family.
Posizione cellulare
Cytoplasm > Cytoskeleton.
Associates with a subset of microtubule plus ends. Enriched in neuronal growth cones (By similarity).
