P4HA1 è un gene codificato dal simbolo P4HA1. Comunemente indicato anche come: Prolyl 4-hydroxylase subunit alpha-1; 4-PH alpha-1; Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-1; P4HA. P4HA1 ha una massa di 61.05kDa e una lunghezza di amminoacidi di 534.
Offriamo 2 anticorpi contro P4HA1, allevati nel Coniglio e Capra, che sono adatti per WB, IHC, ELISA e ICC/IF con campioni derivati da Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
Sommario di Entrez
This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described.
Somiglianze di sequenza
Belongs to the P4HA family.
Posizione cellulare
Endoplasmic reticulum lumen.
