PGRPS è un gene codificato dal simbolo PGLYRP1. Comunemente indicato anche come: Peptidoglycan recognition protein 1; Peptidoglycan recognition protein short; PGRP-S; PGLYRP1; PGLYRP; PGRP; TNFSF3L. PGRPS ha una massa di 21.73kDa e una lunghezza di amminoacidi di 196.
Offriamo 5 anticorpi contro PGRPS, allevati nel Coniglio e Capra, che sono adatti per WB, IHC, ELISA e Citometria a Flusso con campioni derivati da Umano.
Informazioni su geni e proteine
Riepilogo UniProt
Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria, and has bacteriostatic activity towards Gram-negative bacteria. Plays a role in innate immunity.
Specificità del tessuto
Highly expressed in bone marrow. Weak expression found in kidney, liver, small intestine, spleen, thymus, peripheral leukocyte, lung, fetal spleen and neutrophils.
Somiglianze di sequenza
Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.
Modifica post-translazionale
N-glycosylated. N-glycosylation is required for bactericidal activity.
Posizione cellulare
Secreted. Cytoplasmic granule.
