PKA regulatory subunit I beta è un gene codificato dal simbolo PRKAR1B. Comunemente indicato anche come: cAMP-dependent protein kinase type I-beta regulatory subunit; PRKAR1B. PKA regulatory subunit I beta ha una massa di 43.07kDa e una lunghezza di amminoacidi di 381.
Offriamo 3 anticorpi contro PKA regulatory subunit I beta, allevati nel Coniglio, che sono adatti per WB, IHC e ELISA con campioni derivati da Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells.
Sommario di Entrez
The protein encoded by this gene is a regulatory subunit of cyclic AMP-dependent protein kinase A (PKA), which is involved in the signaling pathway of the second messenger cAMP. Two regulatory and two catalytic subunits form the PKA holoenzyme, disbands after cAMP binding. The holoenzyme is involved in many cellular events, including ion transport, metabolism, and transcription. Several transcript variants encoding the same protein have been found for this gene.
Specificità del tessuto
Four types of regulatory chains are found: I-alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible.
Somiglianze di sequenza
Belongs to the cAMP-dependent kinase regulatory chain family.
Modifica post-translazionale
The pseudophosphorylation site binds to the substrate-binding region of the catalytic chain, resulting in the inhibition of its activity.
Posizione cellulare
Cell membrane.
