Sec24C è un gene codificato dal simbolo SEC24C. È noto anche come: Protein transport protein SEC24-related protein C; KIAA0079. Sec24C ha una massa di 118.33kDa e una lunghezza di amminoacidi di 1094.
Offriamo 5 anticorpi contro Sec24C, allevati nel Coniglio, che sono adatti per WB, IHC, ELISA, ICC/IF e IP con campioni derivati da Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex (PubMed:10214955, PubMed:17499046, PubMed:18843296, PubMed:20427317). Plays a central role in cargo selection within the COPII complex and together with SEC24D may have a different specificity compared to SEC24A and SEC24B (PubMed:17499046, PubMed:20427317, PubMed:18843296). May more specifically package GPI-anchored proteins through the cargo receptor TMED10 (PubMed:20427317). May also be specific for IxM motif-containing cargos like the SNAREs GOSR2 and STX5 (PubMed:18843296).
Sommario di Entrez
The protein encoded by this gene is a member of the SEC24 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec24p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The product of this gene may play a role in shaping the vesicle, as well as in cargo selection and concentration. Alternatively spliced transcript variants encoding the same protein have been identified.
Specificità del tessuto
Ubiquitous.
Somiglianze di sequenza
Belongs to the SEC23/SEC24 family. SEC24 subfamily.
Posizione cellulare
Cytoplasmic vesicle > COPII-coated vesicle membrane. Endoplasmic reticulum membrane. Cytoplasm > Cytosol.
