SLC10A1 è un gene codificato dal simbolo SLC10A1. È noto anche come: Sodium/bile acid cotransporter; Cell growth-inhibiting gene 29 protein; Na(+)/bile acid cotransporter; Na(+)/taurocholate transport protein; Sodium/taurocholate cotransporting polypeptide; Solute carrier family 10 member 1; NTCP. SLC10A1 ha una massa di 38.12kDa e una lunghezza di amminoacidi di 349.
Offriamo 3 anticorpi contro SLC10A1, allevati nel Coniglio, che sono adatti per WB, IHC e ELISA con campioni derivati da Umano.
Informazioni su geni e proteine
Riepilogo UniProt
The hepatic sodium/bile acid uptake system exhibits broad substrate specificity and transports various non-bile acid organic compounds as well. It is strictly dependent on the extracellular presence of sodium.
Sommario di Entrez
The protein encoded by this gene belongs to the sodium/bile acid cotransporter family, which are integral membrane glycoproteins that participate in the enterohepatic circulation of bile acids. Two homologous transporters are involved in the reabsorption of bile acids; the ileal sodium/bile acid cotransporter with an apical cell localization that absorbs bile acids from the intestinal lumen, bile duct and kidney, and the liver-specific sodium/bile acid cotransporter, represented by this protein, that is found in the basolateral membranes of hepatocytes. Bile acids are the catabolic product of cholesterol metabolism, hence this protein is important for cholesterol homeostasis.
Somiglianze di sequenza
Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
Posizione cellulare
Membrane.
