SLC16A3 è un gene codificato dal simbolo SLC16A3. È noto anche come: Monocarboxylate transporter 4; MCT 4; Solute carrier family 16 member 3; MCT4. SLC16A3 ha una massa di 49.47kDa e una lunghezza di amminoacidi di 465.
Offriamo 2 anticorpi contro SLC16A3, allevati nel Coniglio, che sono adatti per WB, IHC e ELISA con campioni derivati da Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate (By similarity).
Sommario di Entrez
Lactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton-linked monocarboxylate transporter (MCT) family, which has been designated solute carrier family-16. Each MCT appears to have slightly different substrate and inhibitor specificities and transport kinetics, which are related to the metabolic requirements of the tissues in which it is found. The MCTs, which include MCT1 (SLC16A1; MIM 600682) and MCT2 (SLC16A7; MIM 603654), are characterized by 12 predicted transmembrane domains (Price et al., 1998
Specificità del tessuto
Highly expressed in skeletal muscle.
Somiglianze di sequenza
Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
Posizione cellulare
Cell membrane.
