CD80 è un gene codificato dal simbolo CD80. Altri nomi includono: T-lymphocyte activation antigen Activation B7-1 antigen; BB1; CTLA-4 counter-receptor B7.1; B7; CD28LG; CD28LG1; LAB7. CD80 ha una massa di 33.05kDa e una lunghezza di amminoacidi di 288.
Offriamo 5 proteine CD80
Informazioni su geni e proteine
Riepilogo UniProt
Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation.
Sommario di Entrez
The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy.
Specificità del tessuto
Expressed on activated B-cells, macrophages and dendritic cells.
Posizione cellulare
Membrane.
