LCN1 è un gene codificato dal simbolo LCN1. Comunemente indicato anche come: Lipocalin-1; Tear lipocalin; Tlc; Tear prealbumin; TP; von Ebner gland protein; VEG protein; VEGP. LCN1 ha una massa di 19.25kDa e una lunghezza di amminoacidi di 176.
Offriamo 1 proteine LCN1
Informazioni su geni e proteine
Riepilogo UniProt
Could play a role in taste reception. Could be necessary for the concentration and delivery of sapid molecules in the gustatory system. Can bind various ligands, with chemical structures ranging from lipids and retinoids to the macrocyclic antibiotic rifampicin and even to microbial siderophores. Exhibits an extremely wide ligand pocket.
Sommario di Entrez
This gene encodes a member of the lipocalin family of small secretory proteins. Lipocalins are extracellular transport proteins that bind to a variety of hydrophobic ligands. The encoded protein is the primary lipid binding protein in tears and is overproduced in response to multiple stimuli including infection and stress. The encoded protein may be a marker for chromosome aneuploidy as well as an autoantigen in Sjogren's syndrome. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and two pseudogenes of this gene are also located on the long arm of chromosome 9.
Specificità del tessuto
Mainly expressed in lachrymal and salivary glands. Also expressed in the prostate.
Somiglianze di sequenza
Belongs to the calycin superfamily. Lipocalin family.
Posizione cellulare
Secreted.
