Lymphotactin è un gene codificato dal simbolo XCL1. Comunemente indicato anche come: ATAC; C motif chemokine 1; Cytokine SCM-1; Lymphotaxin; SCM-1-alpha; Small-inducible cytokine C1; XC chemokine ligand 1; XCL1; LTN; SCYC1. Lymphotactin ha una massa di 12.52kDa e una lunghezza di amminoacidi di 114.
Offriamo 2 proteine Lymphotactin
Informazioni su geni e proteine
Riepilogo UniProt
Chemotactic activity for lymphocytes but not for monocytes or neutrophils. In thymus, mediates medullary accumulation of thymic dendritic cells and contributes to regulatoy T cell development, playing a role in self-tolerance establishment.
Sommario di Entrez
This antimicrobial gene encodes a member of the chemokine superfamily. Chemokines function in inflammatory and immunological responses, inducing leukocyte migration and activation. The encoded protein is a member of the C-chemokine subfamily, retaining only two of four cysteines conserved in other chemokines, and is thought to be specifically chemotactic for T cells. This gene and a closely related family member are located on the long arm of chromosome 1.
Specificità del tessuto
Highest level in spleen, lower in peripheral leukocytes and very low levels in lung, colon and small intestine.
Somiglianze di sequenza
Belongs to the intercrine gamma family.
Posizione cellulare
Secreted.
