Anti-RBP4 Anticorpo [RBP4/4048] (A249853)

Name: Anti-RBP4 Antibody [RBP4/4048]
Brand: Antibodies.com
SKU: A249853
Price: 525.0 USD
Availability: InStock

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$525

Anticorpo monoclonale [RBP4/4048] di topo contro RBP4 per IHC-P.

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Alternative Formats and ConjugatesAlternative Formats

Carrier Free and Preservative Free

Consegna

Spese di spedizione

$40

Tempi di consegna

4-6 Giorni lavorativi

Contattaci

Telefono

+1 (314) 370-6046

E-mail

orders@antibodies.com

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Tag dei prodotti:

Anticorpo Monospecifico

Descrizione Prodotto

Nome

Anti-RBP4 Antibody [RBP4/4048]

Descrizione

Mouse monoclonal [RBP4/4048] antibody to RBP4.

Specificità

Retinol (Vitamin A) is transported in the blood bound to its carrier protein, retinol-binding protein (RBP), also designated plasma retinol-binding protein (PRBP) or RBP4. A member of the lipocalin family, RBP conveys retinol from stores in the liver to peripheral tissues. In plasma, RBP binds transthyretin (TTR, formerly called prealbumin) to prevent glomerular filtration of low molecular weight RBP in the kidneys. The stability of this complex holds diagnostic importance because the molar ratio of RBP:TTR provides an indirect way to indicate marginal Vitamin A deficiency. Vitamin A deficiency blocks the secretion of RBP, resulting in defective delivery and supply to epidermal cells. Originally identified solely as a transporter protein, recent studies correlating increased levels of RBP expression in adipose tissue with Insulin resistance have generated research into the possible roles the protein may play in the pathogenesis of type 2 diabetes and obesity.

Applicazioni

IHC-P

Diluizioni consigliate

IHC-P: 1-2 µg/ml

Reattività

Human

Immunogeno

Recombinant fragment, around amino acids 29-148, of human RBP4 protein. The exact sequence is proprietary.

Specie ospite

Mouse

Clonalità

Monoclonal

Clona ID

RBP4/4048

Isotipo

IgG2b

Catene leggere

kappa

Coniugare

Unconjugated

Purificazione

Protein A/G chromatography.

Concentrazione

200 µg/ml

Peso molecolare

25 kDa

Forma del prodotto

Liquid

Formulazione

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Conservazione

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Note generali

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-RBP4 Antibody [RBP4/4048] - BSA and Azide free (A253033).

Sinonimi

OTTHUMP00000020114, OTTHUMP00000020115, OTTHUMP00000020116, Plasma retinol binding protein 4, Plasma retinol-binding protein, Plasma retinol-binding protein(1-176), PRBP, PRO2222, RBP, RDCCAS, RET4_HUMAN, Retinol binding protein 4, Retinol binding protein 4 interstitial, Retinol binding protein 4 plasma

Controlli isotipo

Secondari adatti

Dichiarazione di non responsabilità

Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

Immagini (3)

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Figure 1: Immunohistochemistry - Anti-RBP4 Antibody [RBP4/4048] (A249853)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human kidney using Anti-RBP4 Antibody [RBP4/4048].

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Figure 2: Immunohistochemistry - Anti-RBP4 Antibody [RBP4/4048] (A249853)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human kidney using Anti-RBP4 Antibody [RBP4/4048].

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Figure 3: Anti-RBP4 Antibody [RBP4/4048] (A249853)

Analysis of protein array containing more than 19,000 full-length human proteins using Anti-RBP4 Antibody [RBP4/4048]. Z-Score and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProt^TM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProt^TM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target; a MAb is considered to be specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.