Ricombinante SARS-CoV-2 Spike proteinaa (B.1.351 Variant) (Funzionale) (A269990)

Nome
Recombinant SARS-CoV-2 Spike Protein (B.1.351 Variant) (Functional)
Descrizione
Full-length soluble protein with foldon trimerization motif, mutated Furin recognition site and 4 stabilising mutations (A892P, A942P, K986P and V987P), based on/modified from Amanat et al, 2020 (PMID: 32398876) and Hsieh et al, 2020 (PMID: 32703906).
Applicazioni
WB, SDS-PAGE, Immunoassays, Functional Studies
Sistema di espressione
HEK293 cells.
Specie proteiche
SARS-CoV-2
Lunghezza
Protein fragment.
Sequenza
VNFTTRTQLPPAYTNSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVSGTNGTKRFANPVLPFNDGVYFASTEKSNIIRGWIFGTTLDSKTQSLLIVNNATNVVIKVCEFQFCNDPFLGVYYHKNNKSWMESEFRVYSSANNCTFEYVSQPFLMDLEGKQGNFKNLREFVFKNIDGYFKIYSKHTPINLVRGLPQGFSALEPLVDLPIGINITRFQTLHISYLTPGDSSSGWTAGAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGNIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVKGFNCYFPLQSYGFQPTYGVGYQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFGRDIADTTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQGVNCTEVPVAIHADQLTPTWRVYSTGSNVFQTRAGCLIGAEHVNNSYECDIPIGAGICASYQTQTNSPRGAGSVASQSIIAYTMSLGVENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDFGGFNFSQILPDPSKPSKRSFIEDLLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGPALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTPSALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDPPEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDGKAHFPREGVFVSNGTHWFVTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYDPLQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQYIKSGGSGYIPEAPRDGQAYVRKDGEWVLLSTFLGSHHHHHHHH
Aminoacidi
16 to 1211
Etichetta
His Tag (8xHis at the C-terminus).
MW previsto
137 kDa (including tags).
Biologicamente attivo
Yes
Purezza
> 95% (by SDS-PAGE).
Purificazione
Affinity chromatography.
Forma del prodotto
Liquid
Concentrazione
Lot specific.
Formulazione
Supplied in Phosphate Buffered Saline with 20% Glycerol.
Livello di endotossina
< 0.1 ng/µg (1 IEU/µg), as measured by LAL method.
Conservazione
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -70°C. Avoid freeze / thaw cycles.
Dichiarazione di non responsabilità
Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.
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