Anti-SMNDC1 Anticorpo [PCRP-SMNDC1-1A9] (A248099)

Anticorpo monoclonale [PCRP-SMNDC1-1A9] di topo contro SMNDC1 per Flow Cytometry e IF.

Alternative Formats and ConjugatesAlternative Formats

Spese di spedizione
Tempi di consegna
4-6 Giorni lavorativi
Telefono
+1 (314) 370-6046
Lun - Ven, 8:00 - 16:00 AST
E-mail
orders@antibodies.com
Nome
Anti-SMNDC1 Antibody [PCRP-SMNDC1-1A9]
Descrizione
Mouse monoclonal [PCRP-SMNDC1-1A9] antibody to SMNDC1.
Specificità
SPF30 (survival of motor neuron-related-splicing factor 30), also known as SMNDC1 (survival motor neuron domain containing 1) or SMNR (SMN-related protein), is an essential splicing factor required for spliceosome assembly that belongs to the SMN family. It contains one Tudor domain with significant similarity to SMN (survival motor neuron) and is expressed in skeletal muscle, pancreas and heart, localizing to Cajal bodies and nuclear speckles. SPF30 plays an important role in spliceosome assembly and directly interacts with five U snRNPs. The loss of SPF30 causes spliceosome assembly to arrest at prespliceosomes (A complex). This supports a function for SPF30 in mediating the incorporation/recruitment of U4/U5/U6 tri-snRNP to the prespliceosome. In addition, the overexpression of SPF30 can lead to apoptosis.
Applicazioni
Flow Cytometry, IF
Diluizioni consigliate
Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml
Reattività
Human
Immunogeno
Recombinant full-length human SMNDC1 protein.
Specie ospite
Mouse
Clonalità
Monoclonal
Clona ID
PCRP-SMNDC1-1A9
Isotipo
IgG2b
Coniugare

Unconjugated

Purificazione
Protein A/G chromatography.
Concentrazione
200 µg/ml
Peso molecolare
30 kDa
Forma del prodotto
Liquid
Formulazione
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Conservazione
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Note generali
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-SMNDC1 Antibody [PCRP-SMNDC1-1A9] - BSA and Azide free (A251282).
Sinonimi
30 kDa splicing factor SMNrp, MGC106917, MGC112663, SMN related protein, SMN-related protein, SMNR, SPF30, SPF30_HUMAN, Splicing factor 30, survival of motor neuron-related, Survival motor neuron domain containing 1, Survival motor neuron domain containing protein 1, Survival motor neuron domain-containing protein 1, Survival of motor neuron related splicing factor 30, Survival of motor neuron-related-splicing factor 30
Dichiarazione di non responsabilità
Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

Prodotti alternativi a Anti-SMNDC1 Anticorpo [PCRP-SMNDC1-1A9] (A248099)

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