Anti-Steroidogenic Factor 1 Anticorpo [NR5A1/3420] (A278207)

Anticorpo monoclonale [NR5A1/3420] di topo contro Steroidogenic Factor 1 per IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Spese di spedizione
Tempi di consegna
4-6 Giorni lavorativi
Telefono
+1 (314) 370-6046
Lun - Ven, 8:00 - 16:00 AST
E-mail
orders@antibodies.com
Nome
Anti-Steroidogenic Factor 1 Antibody [NR5A1/3420] - BSA and Azide free
Descrizione
Mouse monoclonal [NR5A1/3420] antibody to Steroidogenic Factor 1.
Specificità
The protein encoded by this gene is a transcriptional activator involved in sex determination. The encoded protein binds DNA as a monomer. Defects in this gene are a cause of XY sex reversal with or without adrenal failure as well as adrenocortical insufficiency without ovarian defect. Steroidogenic Factor 1 (SF-1) is considered an orphan nuclear receptor that belongs to subfamily 5. It was found to be a regulator of steroidogenic enzyme gene expression. Oxysterols are suggested as its ligands. It is expressed in all steroidogenic tissues, including the adrenal cortex, testicular Sertoli cells, and Leydig cells, ovarian theca, hypothalamus, and anterior pituitary. SF-1 plays an important role in adrenal and gonadal development. SF-1 is highly valuable marker to determine the adrenocortical origin of an adrenal mass.
Applicazioni
IHC-P
Diluizioni consigliate
IHC-P: 1-2 µg/ml
Reattività
Human
Immunogeno
Recombinant fragment, around amino acids 220-461, of human Steroidogenic Factor 1 protein. The exact sequence is proprietary.
Specie ospite
Mouse
Clonalità
Monoclonal
Clona ID
NR5A1/3420
Isotipo
IgG2b
Catene leggere
kappa
Coniugare

Unconjugated

Purificazione
Protein A/G chromatography.
Concentrazione
1 mg/ml
Peso molecolare
53 kDa
Forma del prodotto
Liquid
Formulazione
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Conservazione
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Note generali
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-Steroidogenic Factor 1 Antibody [NR5A1/3420] (A277619).
Sinonimi
AD4BP, Adrenal 4 binding protein, Adrenal 4-binding protein, ELP, FTZ 1, FTZ1, FTZF 1, FTZF1, Fushi tarazu factor (Drosophila) homolog 1, Fushi tarazu factor homolog 1, hSF 1, NR5A1, Nuclear receptor AdBP4, Nuclear receptor subfamily 5 group A member 1, POF7, SF 1, SF-1, SF1, SPGF8, SRXY3, Steroid hormone receptor Ad4BP, Steroidogenic factor 1 nuclear receptor, STF 1, STF-1, STF1, STF1_HUMAN
Dichiarazione di non responsabilità
Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

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