Anti-VEGF Receptor 2 Anticorpo [DC101] (A254014)

Anticorpo monoclonale [DC101] di ratto contro VEGF Receptor 2 per WB e Neutralization Studies.

Alternative Formats and ConjugatesAlternative Formats

Spese di spedizione
Tempi di consegna
4-6 Giorni lavorativi
Telefono
+1 (314) 370-6046
Lun - Ven, 8:00 - 16:00 AST
E-mail
orders@antibodies.com
Nome
Anti-VEGF Receptor 2 Antibody [DC101] - BSA and Azide free
Descrizione
Rat monoclonal [DC101] antibody to VEGF Receptor 2.
Specificità
This antibody is specific to Mouse VEGFR2/FLK-1/CD309 and does not cross-react with FLK-2. VEGFR2 is a type I transmembrane glycoprotein. It is a member of the CSF-1/PDGF receptor family of type III tyrosine kinase receptors. Endothelial cells, embryonic tissues, and megakaryocytes mainly express VEGFR2. It plays an important role in the regulation of angiogenesis, vasculogenesis, and vascular permeability. The ligands of VEGFR2 include VEGF-A, VEGF-C, VEGF-D, and VEGF splice isoforms. Ligation of VEGFR2 with its ligands results in the receptor dimerization and auto-phosphorylation, stimulating endothelial cell proliferation and migration.
Applicazioni
WB, Neutralization Studies
Diluizioni consigliate
WB (non-reducing): 2-5 µg/ml
Reattività
Mouse
Immunogeno
Recombinant full-length mouse VEGFR2 protein.
Specie ospite
Rat
Clonalità
Monoclonal
Clona ID
DC101
Isotipo
IgG1
Catene leggere
kappa
Coniugare

Unconjugated

Purificazione
Protein A/G chromatography.
Concentrazione
1 mg/ml
Peso molecolare
180-190 kDa
Forma del prodotto
Liquid
Formulazione
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Conservazione
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Note generali

This antibody blocks binding of VEGF to VEGF-R2, inhibits VEGF-induced signaling, and blocks tumor growth in mice.

This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-VEGF Receptor 2 Antibody [DC101] (A250834).

Sinonimi
CD309, CD309 antigen, EC 2.7.10.1, Fetal liver kinase 1, FLK-1, FLK1, FLK1, mouse, homolog of, Kdr, Kinase insert domain receptor, Kinase insert domain receptor (a type III receptor tyrosine kinase), KRD1, Ly73, Protein tyrosine kinase receptor FLK1, Protein-tyrosine kinase receptor flk-1, soluble VEGFR2, Tyrosine kinase growth factor receptor, Vascular endothelial growth factor receptor 2, VEGFR, VEGFR 2, VEGFR-2, VEGFR2, VGFR2_HUMAN
Dichiarazione di non responsabilità
Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

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