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Anti-MAPRE1 (EB1) Antibody

Rat monoclonal (KT51) antibody to MAPRE1 (EB1) from Absea Biotechnology (010811B11).
Name: Anti-MAPRE1 (EB1) Antibody
Description: Rat monoclonal (KT51) antibody to MAPRE1 (EB1).
Applications: WB, IP, IF
Reactivity: Mouse, Human, Ape and Hamster
Immunogen: The C-terminal part of mouse EB1 (amino acids 125-268).
Amino Acid Start: 177
Amino Acid End: 420
Host: Rat
Clonality: Monoclonal
Clone: KT51
Isotype: IgG2a
Conjugate: Unconjugated
Purification: Antibody is purified from culture supernatant using a protein G column.
Concentration: 1 mg/ml in PBS containing 0.09% sodium azide as a preservative.
Storage: 4 °C for 1 month, -20 °C or -80°C in aliquots. Avoid repeated freeze/thaw cycles.

Function: Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes cytoplasmic microtubule nucleation and elongation. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes (By similarity). May play a role in cell migration.
Tissue Specificity: Expressed within the midpiece of sperm tail (at protein level).
Sequence Similarities: Belongs to the MAPRE family.
Cellular Location: Cytoplasm. Cytoplasm > Cytoskeleton. Cytoplasm > Cytoskeleton > Microtubule organizing center > Centrosome.

Associated with the microtubule network at the growing distal tip of microtubules. Detected along microtubules (PubMed:21357749). Also enriched at the centrosome (By similarity).
UniProt: Q61166
Gene ID: 13589
Synonyms: 5530600P05Rik Antibody
Adenomatous polyposis coli binding protein EB 1 Antibody
Adenomatous polyposis coli binding protein EB1 Antibody
AI462499 Antibody
AI504412 Antibody
APC binding protein EB 1 Antibody
APC binding protein EB1 Antibody
APC-binding protein EB1 Antibody
AW260097 Antibody
BIM1p Antibody
D2Ertd459e Antibody
EB 1 Antibody
EB1 Antibody
End binding protein 1 Antibody
End-binding protein 1 Antibody
fa01e12 Antibody
fc23e11 Antibody
fi33c06 Antibody
MAPRE 1 Antibody
Mapre3 Antibody
MARE1_HUMAN Antibody
MGC117374 Antibody
MGC129946 Antibody
MGC52508 Antibody
Microtubule associated protein RP/EB family member 1 Antibody
Microtubule-associated protein RP/EB family member 1 Antibody
wu:fa01e12 Antibody
wu:fc23e11 Antibody
wu:fi33c06 Antibody
zgc:55428 Antibody
zgc:77807 Antibody
zgc:85755 Antibody
Information: Target information shown above is from the UniProt Consortium.

Specific Citations

Herter JM et al. AKAP9 regulates activation-induced retention of T lymphocytes at sites of inflammation. Nat Commun 6: 10182 (2015)

Kanfer G et al. Mitotic redistribution of the mitochondrial network by Miro and Cenp-F. Nat Commun 6: 8015 (2015)

Arens J et al. A morphometric screen identifies specific roles for microtubule-regulating genes in neuronal development of P19 stem cells. PLoS One 8(11): e79796 (2013)

Woods KL et al. Recruitment of EB1, a master regulator of microtubule dynamics, to the surface of the Theileria annulata schizont. PLoS Pathog 9(5): e1003346 (2013)

Komorova Y et al. Mammalian end binding proteins control persistent microtubule growth. J Cell Biol 184(5): 691-706 (2009)

Komarova Y et al. EB1 and EB3 control CLIP dissociation from the ends of growing microtubules. Mol. Biol. Cell. 16(11): 5334-45 (2005)

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Please Note: Anti-MAPRE1 (EB1) Antibody is for research use only. It is not intended for diagnostic of therapeutic use.
Antibodies.com | 010811B11
Size Price Quantity
100µg £186
200µg £273
1mg £730

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