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Anti-PAI-1 Antibody

Rabbit polyclonal antibody to PAI-1 from ABclonal (A1297).
Name: Anti-PAI-1 Antibody
Description: Rabbit polyclonal antibody to PAI-1.
Applications: WB
Dilutions: WB: 1:500 - 1:2000.
Reactivity: Human
Immunogen: A synthetic peptide of human SERPINE1.
Protein Length: 402
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Affinity purification.
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Serine protease inhibitor. This inhibitor acts as 'bait' for tissue plasminogen activator, urokinase, protein C and matriptase-3/TMPRSS7. Its rapid interaction with PLAT may function as a major control point in the regulation of fibrinolysis.
Tissue Specificity: Found in plasma and platelets and in endothelial, hepatoma and fibrosarcoma cells.
Involvement in Disease: Plasminogen activator inhibitor-1 deficiency: A hematologic disorder characterized by increased bleeding after trauma, injury, or surgery. Affected females have menorrhagia. The bleeding defect is due to increased fibrinolysis of fibrin blood clots due to deficiency of plasminogen activator inhibitor-1, which inhibits tissue and urinary activators of plasminogen.
Sequence Similarities: Belongs to the serpin family.
Post-Translational Modification: Inactivated by proteolytic attack of the urokinase-type (u-PA) and the tissue-type (TPA), cleaving the 369-Arg-|-Met-370 bond.
Cellular Location: Secreted.
UniProt: P05121
Gene ID: 5054
Synonyms: Clade E Antibody
Endothelial plasminogen activator inhibitor Antibody
Nexin Antibody
PAI Antibody
PAI 1 Antibody
PAI1 Antibody
PAI1_HUMAN Antibody
PLANH1 Antibody
Plasminogen activator inhibitor 1 Antibody
Plasminogen activator inhibitor type 1 Antibody
Serine (or cysteine) proteinase inhibitor Antibody
Serine (or cysteine) proteinase inhibitor clade E (nexin plasminogen activator inhibitor type 1) member 1 Antibody
Serpin E1 Antibody
Serpin peptidase inhibitor clade E Antibody
Serpin peptidase inhibitor clade E (nexin plasminogen activator inhibitor type 1) member 1 Antibody
Serpine 1 Antibody
SERPINE1 Antibody
Information: Target information shown above is from the UniProt Consortium.
Western blot analysis of extracts of various cells, using SERPINE1 antibody.
Please Note: All batches are extensively validated and are guaranteed to work as specified, however, QC data is not necessarily from the current lot on sale.
Total Citations (1)
Description: Goat polyclonal antibody to SERPINE1.
Application: ELISA, WB, IHC, EIA
Host: Goat
Isotype: IgG
Reactivity: Human

£205

Total Citations (3)
Description: Rabbit polyclonal antibody to PAI-1 (N315)
Application: WB, IHC
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide, corresponding to amino acids 281-330 of Human PAI-1.

£165 – £283

Description: Rabbit polyclonal antibody to PAI-1
Application: WB, IHC, ELISA
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: Synthesized peptide derived from the Internal region of human PAI-1.

£180 – £234

Description: Rabbit polyclonal antibody to SERPINE1
Application: IHC
Host: Rabbit
Reactivity: Human
Immunogen: Fusion protein corresponding to a region derived from internal residues of human serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

£234

Please Note: Anti-PAI-1 Antibody is for research use only. It is not intended for diagnostic or therapeutic use.
Antibodies.com | A1297
Size Price Quantity
100µl £243
200µl £372

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Lead Time: Currently 4-6 Days
Shipping Information
  • £20 to United Kingdom
  • £35 to Europe