Cytokines play crucial roles in regulating various immune responses, and their dysregulation can contribute to the development and progression of cancer. Some critical cytokines involved in cancer include: 1) Interleukin-2 (IL-2). IL-2 is a potent immune stimulatory cytokine that promotes the activation and proliferation of T cells and natural killer (NK) cells. It has been used in cancer immunotherapy to enhance the immune response against tumours; 2) Interferons (IFNs). Interferons are a group of cytokines that possess antiviral, immunomodulatory, and anti-proliferative properties. IFN-alpha and IFN-beta are used in the treatment of certain cancers, including melanoma and leukemia, due to their ability to inhibit tumour cell growth and enhance immune anti-tumour responses; 3) Tumour necrosis factor-alpha (TNF-alpha). TNF-alpha is a pro-inflammatory cytokine that can induce cell death (apoptosis) in some tumour cells. It also plays a role in promoting inflammation and recruiting immune cells to the tumour microenvironment; 4) Transforming growth factor-beta (TGF-beta). TGF-beta has dual roles in cancer. In early stages, it acts as a tumour suppressor by inhibiting cell proliferation and promoting apoptosis. However, in later stages, it can promote tumour progression by suppressing immune responses and promoting tumour invasion and metastasis; 5) Interleukin-10 (IL-10). IL-10 is an immunosuppressive cytokine that can inhibit immune responses. In cancer, high levels of IL-10 can inhibit anti-tumour immune responses, leading to immune evasion by tumour cells; 6) Interleukin-12 (IL-12). IL-12 is an important cytokine involved in the activation of immune cells, particularly T cells and NK cells. It enhances the production of interferon-gamma (IFN-gamma) and promotes anti-tumour immune responses; 7) Interleukin-6 (IL-6). IL-6 is a pleiotropic cytokine that plays complex roles in cancer. It can have both pro- and anti-tumour effects depending on the context. Elevated levels of IL-6 have been associated with tumour growth, angiogenesis, and metastasis in various cancers. We provide a wide product catalogue of research reagents for studying cytokines, including Interferon gamma antibodies, IL2 antibodies, IL6 antibodies, IL6 ELISA Kits, and IL10 ELISA Kits. Explore our full cytokines product range below and discover more, for less. Alternatively, you can explore our Interleukins, Interferons, and TNF product ranges.