Heart

The heart is the central pumping muscle of the circulatory system, supplying oxygen and nutrients to all parts of the body. Composed of specialized cardiac muscle cells (cardiomyocytes), connective tissue, and various other cell types, the heart performs its function through coordinated electrical impulses resulting in mechanical muscle contractions. Cardiomyocytes are the predominant cells of the heart, responsible for its rhythmic contractions. They are branched and interconnected, forming a syncytium that allows electrical signals to travel rapidly through the heart. Cardiomyocytes contract in response to electrical stimulation, generating the heart’s pumping action. The heart's electrical activity is coordinated by specialized cells in the conducting system. The sinoatrial (SA) node (pacemaker) initiates the heart’s electrical impulses and is composed of specialized cardiac muscle (nodal) cells located in the right atrium of the heart. It initiates and regulates the heart's rhythmic contractions. The atrioventricular (AV) node is responsible for transmitting electrical signals from the atria to the ventricles. The AV node is also composed of specialized cardiac muscle cells that allow them to function as a relay point between the atria and the ventricles. Nodal cells within the AV node have a slower conduction velocity, allowing the atria to contract and pump blood into the ventricles before the ventricles contract, ensuring efficient pumping of blood. This coordination helps optimize the heart's pumping efficiency and prevents chaotic electrical activity. The AV node is connected to the ventricles via the Bundle of His (atrioventricular bundle) and Purkinje fibres. Connective tissue in the heart is composed of fibroblasts, which provide structural support, and contribute to wound healing and scar formation after injury, whilst the inner lining of the heart chambers and blood vessels consists of endothelial cells. These cells help maintain the smooth surface necessary for blood flow, prevent clot formation, and regulate the passage of molecules between the blood and surrounding tissues. Blood vessels within the heart (coronary arteries and arterioles) also contain smooth muscle cells that regulate blood flow by constricting or dilating heart vessels. Finally, the heart also contains immune cells that monitor and protect the organ against infections and tissue damage. These cells are particularly important in cases of inflammation and injury. The primary function of the heart is to pump blood throughout the body to deliver oxygen and nutrients to cells and remove waste products. Blood returning from the body enters the right atrium and oxygenated blood enters the left atrium. Atria then contract, pushing blood into the ventricles which then contract, pumping blood into the pulmonary artery (right ventricle) and aorta (left ventricle). This sends oxygen-depleted blood to the lungs for oxygenation and oxygen-rich blood to the body's tissues. The cardiac cycle comprises systole (contraction) and diastole (relaxation) phases of the heart chambers. These phases ensure efficient blood flow and allow the heart to refill between beats. Finally, coronary arteries provide oxygen and nutrients to the heart muscle itself. Coronary circulation ensures that the heart has the energy it needs to maintain its pumping action. We provide a large product range of research reagents for investigating heart, including CD34 antibodies, Hsp27 antibodies, Smad4 antibodies, C Reactive Protein ELISA Kits, and STAT3 ELISA Kits. Explore our full heart product range below and discover more, for less. Alternatively, you can explore our Hypertrophy, Cardiogenesis, and Contractility product ranges.

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Western Blot - Anti-LAMP2 Antibody [GL2A7] (A304947) - Antibodies.com
(2)
Western Blot - Anti-alpha smooth muscle Actin Antibody (A82445)
(7)
Western Blot - Anti-SNAIL Antibody (A14826) - Antibodies.com
(4)
Western Blot - Anti-SNAIL Antibody (A84245)
(3)
Immunohistochemistry - Anti-HSP27 Antibody [G3.1] (A248872) - Antibodies.com
(6)
Western Blot - Anti-STAT3 (phospho Ser727) Antibody (A7223) - Antibodies.com
(8)
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Flow Cytometry - Anti-CD34 Antibody [QBEnd-10] - BSA and Azide free (A85654) - Antibodies.com
Immunohistochemistry - Anti-alpha Smooth Muscle Actin Antibody [1A4] (A249894) - Antibodies.com
(4)
Immunohistochemistry - Anti-alpha Smooth Muscle Actin Antibody [1A4] - BSA and Azide free (A253074) - Antibodies.com
(4)
Western Blot - Anti-Glucose Transporter GLUT4 Antibody (A15818) - Antibodies.com
(7)
Western Blot - Anti-Akt2 (phospho Ser474) Antibody (A7006) - Antibodies.com
(4)
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Immunohistochemistry - Anti-alpha Smooth Muscle Actin Antibody [SPM332] (A249895) - Antibodies.com
(3)
Western Blot - Anti-HSF1 Antibody [10H8] (A305101) - Antibodies.com
(5)
Western Blot - Anti-GSK3 beta (phospho Ser9) Antibody (A7098) - Antibodies.com
(8)
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Western Blot - Anti-Notch1 Antibody (A15817) - Antibodies.com
(11)
Immunohistochemistry - Anti-alpha Smooth Muscle Actin Antibody [SPM332] - BSA and Azide free (A253075) - Antibodies.com
(3)
Anti-mTOR (phospho-S2448) Antibody from Bioworld Technology (BS4706) - Antibodies.com
(3)
Western Blot - Anti-STAT3 Antibody (A13365) - Antibodies.com
(11)
Immunohistochemistry - Anti-HSP27 Antibody [8A7] (A304709) - Antibodies.com
(5)
Western Blot - Anti-HDAC1 Antibody (A12564) - Antibodies.com
(8)
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Flow Cytometry - Anti-Notch1 Antibody [mN1A] (A86355) - Antibodies.com
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Immunohistochemistry - Anti-Vinculin Antibody [VCL/3617] (A250291) - Antibodies.com
(6)
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Western Blot - Anti-ACE2 Antibody (A87864) - Antibodies.com
(7)
Western Blot - Anti-alpha smooth muscle Actin Antibody (A89813) - Antibodies.com
(11)
Immunofluorescence - Anti-HSP20 (phospho Ser16) Antibody (A0488) - Antibodies.com
(2)
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Immunohistochemistry - Anti-Vinculin Antibody [VCL/3617] - BSA and Azide free (A253471) - Antibodies.com
(6)
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Western Blot - Anti-AKT2 Antibody (A305096) - Antibodies.com
(2)
Western Blot - Anti-HDAC5 (phospho Ser498) Antibody (A7101) - Antibodies.com
(4)
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Immunohistochemistry - Anti-HSF1 Antibody [10H4] (A305102) - Antibodies.com
(4)
Western Blot - Anti-HSF1 Antibody [4B4] (A305103) - Antibodies.com
(4)
Western Blot - Anti-FHL1 Antibody (A83184)
(2)
Immunohistochemistry - Anti-HSP27 Antibody [G3.1] - BSA and Azide free (A252052) - Antibodies.com
(6)
Immunohistochemistry - Anti-RyR2 (phospho Ser2808) Antibody (A0570) - Antibodies.com
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Western Blot - Anti-KLF4 Antibody (A15314) - Antibodies.com
(4)
Western Blot - Anti-TRIM55 Antibody (A82605) - Antibodies.com
(2)
Western Blot - Anti-ETS1 (phospho Thr38) Antibody (A0478) - Antibodies.com
(5)
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Immunohistochemistry - Anti-HSP27 Antibody [SPM252] (A248873) - Antibodies.com
(6)
Immunohistochemistry - Anti-HSP27 Antibody [HSPB1/774] (A248874) - Antibodies.com
(6)
Western Blot - Anti-Notch1 Antibody (A88025) - Antibodies.com
(10)
Western Blot - Anti-GSK3 beta Antibody (B7098) - Antibodies.com
(8)
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Immunohistochemistry - Anti-HSP27 Antibody [SPM252] - BSA and Azide free (A252053) - Antibodies.com
(6)
Immunohistochemistry - Anti-HSP27 Antibody [HSPB1/774] - BSA and Azide free (A252054) - Antibodies.com
(6)
Western Blot - Anti-mTOR Antibody (A13984) - Antibodies.com
(7)
Western Blot - Anti-HDAC1 Antibody (C0221) - Antibodies.com
(7)
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Western Blot - Anti-STAT3 Antibody (B7224) - Antibodies.com
(8)
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Western Blot - Anti-Nrf2 Antibody (C0279) - Antibodies.com
(5)
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Western Blot - Anti-MYLIP Antibody (C15558) - Antibodies.com
(4)
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Western Blot - Anti-Hexokinase 1 Antibody (A12985) - Antibodies.com
(7)
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Western Blot - Anti-SIRT4 Antibody (A84006) - Antibodies.com
(2)

Showing 1-50 of 3,208 products

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