Glial cells have emerged as critical players in various aspects of brain function. These non-neuronal cells, including astrocytes, oligodendrocytes, and microglia, are essential for maintaining brain homeostasis, supporting neuronal function, and modulating synaptic transmission. Glial cell markers are specific proteins or molecules that serve as important tools in neuroscience research to identify and study different glial cell populations. GFAP is perhaps the most well-known marker for astrocytes, the most abundant glial cell type in the brain. GFAP is a cytoskeletal protein that provides structural support to astrocytes, with increased GFAP expression often associated with astrocytic activation in response to various brain injuries or neurodegenerative diseases. Researchers therefore use GFAP as a marker to study astrocyte reactivity and assess their involvement in neurological disorders. S100B is a calcium-binding protein mainly expressed in astrocytes. It is a widely used marker for astroglial activity and is particularly valuable in studies related to brain injury, neuroinflammation, and neurodegenerative diseases. Elevated levels of S100B in the blood or cerebrospinal fluid are also often also associated with brain damage, making it a potential biomarker for brain injury assessment. Olig2 is a transcription factor primarily expressed by oligodendrocytes, the glial cells responsible for producing the myelin sheaths that insulate neuronal axons. Olig2 is essential for oligodendrocyte development and is used as a marker both to identify oligodendrocyte progenitor cells (OPCs) during brain development, and in studies of remyelination in demyelinating disorders such as multiple sclerosis. MBP is a major structural protein component of the myelin sheath and serves as a specific marker for mature oligodendrocytes. It is widely used to study myelin formation, maintenance, and integrity. Disruptions in MBP expression or myelin structure are associated with a variety of demyelinating diseases and white matter disorders. Iba1 is a marker for microglia, the resident immune cells of the central nervous system. Microglia play a crucial role in neuroinflammation and brain immune responses. Iba1 is therefore used to study microglial activation and morphological changes in various neurological disorders, including neurodegenerative diseases and brain injuries. CD11b and CD45 are cell surface markers that are highly expressed in activated microglia. They are commonly used in flow cytometry and immunohistochemistry to distinguish microglia from other immune cells and to quantify microglial activation levels in the brain. GLT-1, also known as EAAT2 (Excitatory Amino Acid Transporter 2), is a glial cell-specific glutamate transporter predominantly expressed by astrocytes. It is critical for clearing excess glutamate from the synapse, preventing excitotoxicity, and maintaining synaptic transmission. Changes in GLT-1 expression have been implicated in various neurodegenerative diseases and neuropsychiatric disorders. We provide a comprehensive product catalogue of research tools for investigating glia markers, including CD45 antibodies, CD11b antibodies, GFAP antibodies, Myelin Basic Protein ELISA Kits, and GFAP ELISA Kits. Explore our full glia markers product range below and discover more, for less. Alternatively, you can explore our Microglia Marker, Oligodendrocyte Marker, and Astrocyte Marker product ranges.