Recombinant Anti-ACE2 Antibody [ACE2/8748R] (A314431)

$765

Recombinant rabbit monoclonal [ACE2/8748R] antibody to ACE2 for ELISA and IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-ACE2 Antibody [ACE2/8748R]
Description
Recombinant rabbit monoclonal [ACE2/8748R] antibody to ACE2.
Specificity
Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II toangiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. By cleavage ofangiotensin II, may be an important regulator of heart function. By cleavage of angiotensin II, may also have a protective role in acute lung injury. Plays an important role in amino acid transport by acting as binding partner of amino acid transporter SL6A19 in intestine, regulating trafficking, expression on the cell surface, and its catalytic activity In case of human coronaviruses SARS and HCoV-NL63 infections, serve as functional receptor for the spike glycoprotein of both coronaviruses.
Applications
ELISA, IHC-P
Positive Control
Human kidney, heart, testis or small intestine.
Dilutions
IHC: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant fragment (around Amino Acids 705-805) of human ACE2. The exact sequence is proprietary.
Host
Rabbit
Clonality
Monoclonal
Clone ID
ACE2/8748R
Isotype
IgG
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
92 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonyms
ACE 2, ACE related carboxypeptidase, ACE-related carboxypeptidase, ACE2_HUMAN, ACEH, Angiotensin Converting Enzyme 2, Angiotensin converting enzyme homolog, Angiotensin converting enzyme like protein, Angiotensin I Converting Enzyme (peptidyl dipeptidase A) 2, Angiotensin I converting enzyme 2, Angiotensin-converting enzyme homolog, DKFZP434A014, EC 3.4.17, metalloprotease MPROT 15, Metalloprotease MPROT15, OTTHUMP00000022963, Processed angiotensin-converting enzyme 2
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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