Anti-ADAM10 Antibody (A283888)

Anti-ADAM10 Antibody

Rabbit polyclonal antibody to ADAM10.

This antibody recognises human Disintegrin and metalloproteinase domain-containing protein 10, also known as ADAM-10, CDw156, Mammalian disintegrin-metalloprotease, CD156c or Kuzbanian protein homolog. CD156c is a 748 amino acid ~85 kDa type I, single pass transmembrane glycoprotein with a 19 aa signal peptide and adjacent 194 aa propeptide region yeilding a mature 535 aa protease. CD156c is a member of the mammalian ADAM family and is involved in the cleavage of TNF alpha, Notch and its ligand delta.

WB: 1:1,000

Human

A peptide corresponding to amino acids 732-748 of human CD156c.

PQRQRPRESYQMGHMRR

Rabbit

Polyclonal

IgG

Unconjugated

Liquid

Supplied in Phosphate Buffered Saline with 0.02% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Rabbit anti Human CD156c antibody recognizes human Disintegrin and metalloproteinase domain-containing protein 10, also known as ADAM-10, CDw156, Mammalian disintegrin-metalloprotease, CD156c or Kuzbanian protein homolog. CD156c is a 748 amino acid ~85 kDa type I, single pass transmembrane glycoprotein with a 19 aa signal peptide and adjacent 194 aa propeptide region yeilding a mature 535 aa protease. CD156c is a member of the mammalian ADAM family and is involved in the cleavage of TNF alpha, Notch and its ligand delta (Primakoff & Miles 2000).

A disintegrin and metalloprotease domain 10, A disintegrin and metalloproteinase domain 10, AD 10, AD10, AD18, ADA10_HUMAN, ADAM 10, ADAM metallopeptidase domain 10, CD 156c, CD156c, CD156c antigen, CDw156, disintegrin and metalloproteinase domain containing protein 10, Disintegrin and metalloproteinase domain-containing protein 10, HsT 18717, HsT18717, Kuz, Kuzbanian, Kuzbanian protein homolog, Kuzbanian, Drosophila, homolog of, MADM, Mammalian disintegrin metalloprotease, Mammalian disintegrin-metalloprotease, RAK